Recent years have witnessed the great contributions that drug combination therapy has
made for enhanced cancer therapy. However, because of the complicated pharmacokinetics …

Background Doxorubicin (DOX) is one of the most effective treatments for hepatocellular
carcinoma (HCC), but is restricted by its poor pharmacokinetics. Herein, we exploited …

Biomimetic design has been extensively investigated. The only FDA-approved biomimetic
albumin-bound paclitaxel may not be beneficial to some treated patients due to rapid …

Drug delivery has become an important strategy for improving the chemotherapy efficiency.
Here we developed a multifunctionalized nanosized albumin-based drug-delivery system …

The chemotherapy efficacy of nanodrugs is restricted by poor tumor targeting and uptake.
Here, an engineered biohybrid living material (designated as EcN@ HPB) is constructed by …

Prodrug self-nanoassemblies have many advantages for anticancer drug delivery, including
high drug loading rate, resistance to recrystallization, and on-demand drug release …

Doxorubicin (DOX) is a widely-used anticancer drug, but its cardiotoxicity severely hampers
its potency in chemotherapy. Herein, human serum albumin (HSA) is engaged as a …

The synergistic combination of photothermal and RNA interference therapy demonstrates
great potential for effective treatment of metastatic breast cancer, but their efficacy is limited …

We designed a pH intelligently driven self-assembled nano-platform (GOx@ ZIF-OVA). The
nano-platform was composed of glucose oxidase (GOx), ovalbumin (OVA) and zeolitic …

To promote the targeted cancer therapy, the pH-sensitive small molecule nanodrug self-
assembled from amphiphilic vitamin B6-E analogue conjugate was successfully constructed …