Parkinson's disease (PD) is a neurodegenerative disease with unknown cause in the
majority of patients, who are therefore considered “idiopathic”(IPD). PD predominantly …

With the world's population ageing, the incidence of Parkinson's disease (PD) is on the rise.
In recent years, inflammatory processes have emerged as prominent contributors to the …

Parkinson's disease (PD) is the second most common neurodegenerative disorder
worldwide, being characterized by the progressive loss of dopaminergic neurons in the …

Background Abnormal activation of immune system is an important pathogenesis of
Parkinson's disease, but the relationship between peripheral inflammation, central microglia …

Parkinson's disease (PD) is the second most common neurodegenerative disease, with
symptoms such as tremor, bradykinesia with rigidity, and depression appearing in the late …

Peripheral inflammation triggers exacerbation in the central brain′ s ongoing damage in
several neurodegenerative diseases. Systemic inflammatory stimulus induce a general …

Parkinson's disease (PD) is a neurodegenerative movement disorder characterized by the
progressive loss of dopaminergic neurons in the substantia nigra and depletion of dopamine …

Parkinson's disease (PD) is the second most common neurodegenerative disorder among
elderly population, characterized by the progressive degeneration of dopaminergic neurons …

Microglia, often described as the brain-resident macrophages, play crucial roles in central
nervous system development, maintenance, plasticity, and adaptation to the environment …

The impact of systemic inflammation in nigral dopaminergic cell loss remains unclear. Here,
we have investigated the role of peripheral inflammation induced by systemic …