Despite significant technological advances the etiology of cancer and mechanism disease
progression, and their translation into therapeutic benefits has been considerably slow …

In today's fast-paced society, efficiency is critical in many aspects, especially in costly,
resourceintensive processes such as drug discovery and development. Technological …

Simple Summary Drug repurposing is emerging as a promising avenue for addressing
clinical challenges in treating drug-resistant and metastatic cancers. As a case study, some …

Targeted drugs and precision medicine have transformed the landscape of cancer therapy
and significantly improved patient outcomes in many cases. However, as therapies are …

Drug repurposing (an approach to drug development that is also known as drug
repositioning, reprofiling, or retasking) has become a matter of intense interest during the …

Highlights•De novo anticancer drug discovery is challenging and repurposing in oncology is
a promising field.•Drug repositioning increasingly emerges as faster, cheaper and …

The analyses of drug development from different standpoints show how resource-intensive
this process is, with two main disadvantages: time and cost. It takes 11 to 14 years to …

Drug repurposing refers to the identification of clinically approved drugs with the known
safety profiles and defined pharmacokinetic properties for new indications. Despite the …

Simple Summary The repurposing of drugs is an important and rapidly growing field in the
treatment of cancer. The main advantage of drug repurposing is using currently established …

Drug repurposing is at the heart of precision oncology. The move from tissue-or cancer-
specific treatments to genomic-or actionable-target treatments necessarily entails the reuse …