Clinical pharmacodynamics of nebivolol: new evidence of nitric oxide‐mediated vasodilating activity and peculiar haemodynamic properties in hypertensive patients

A Zanchetti - Blood pressure, 2004 - Taylor & Francis
New evidence from recently completed clinical studies performed with nebivolol, a highly
selective beta‐1 β‐blocker, endowed with additional vasodilating activity mediated by nitric …

Experimental evidences of nitric oxide‐dependent vasodilatory activity of nebivolol, a third‐generation β‐blocker

L Ignarro - Blood Pressure, 2004 - Taylor & Francis
Nebivolol is a new and selective β 1‐adrenergic receptor antagonist whose haemodynamic
profile is different from that of classical β‐blockers. The blood pressure lowering effects of …

Nebivolol, a beta blocker of the 3rd generation: modern therapy of arterial hypertension. Results of a multicenter observation study

J Von Fallois, HD Faulhaber - Praxis, 2001 - europepmc.org
Background Nebivolol represents a therapeutic class of beta blockers with high beta 1
selectivity and modulatory effect on vascular reactions by releasing nitric oxide (NO) from …

Nitric oxide mechanisms of nebivolol

A Maffei, G Lembo - Therapeutic advances in cardiovascular …, 2009 - journals.sagepub.com
β-blockers are among the most widely used drugs in the prevention and treatment of
cardiovascular disease, although they are associated with increased peripheral resistance …

Nebivolol: a review of its clinical and pharmacological characteristics.

W Gielen, TJ Cleophas… - International Journal of …, 2006 - search.ebscohost.com
Nebivolol is a cardioselective lipophilic β-blocker devoid of intrinsic sympathomimetic and
membrane-stabilizing actions. The pharmacological profile differs from that of conventional …

Pharmacology of nebivolol

M Mangrella, F Rossi, F FICI, F ROSSI - Pharmacological research, 1998 - Elsevier
Nebivolol is a new selective β1-adrenergic blocking agent, that possesses a peculiar
pharmacodynamic profile and an original chemical structure, by which it differs from …

Nebivolol: a novel beta-blocker with nitric oxide-induced vasodilatation

R Weiss - Vascular health and Risk management, 2006 - Taylor & Francis
Nebivolol is a novel beta1-blocker with a greater degree of selectivity for beta1-adrenergic
receptors than other agents in this class and a nitric oxide (NO)-potentiating, vasodilatory …

A review of the safety and efficacy of nebivolol in the mildly hypertensive patient

C John - Vascular health and risk management, 2007 - Taylor & Francis
Nebivolol is a third generation beta-blocker, which can be distinguished from other beta-
blockers by its hemodynamic profile. It combines beta-adrenergic blocking activity with a …

Nebivolol: A Highly Selective β1‐Adrenergic Receptor Blocker That Causes Vasodilation by Increasing Nitric Oxide

S Gupta, HM Wright - Cardiovascular therapeutics, 2008 - Wiley Online Library
Nebivolol (Bystolic®) is a cardioselective beta 1 (β1)‐adrenergic receptor blocker with
endothelium‐dependent vasodilating properties. The endothelium‐dependent relaxation …

Nebivolol: a review

J Cockcroft - Expert opinion on pharmacotherapy, 2004 - Taylor & Francis
Nebivolol is a vasodilating β-blocker, which can be distinguished from other β-blockers by its
haemodynamic profile. It combines β-adrenergic blocking activity with a vasodilating effect …