Background Francisella tularensis is the causative agent of tularemia and is classified as a
Category A select agent. Recent studies have implicated TLR2 as a critical element in the …

Francisella tularensis, a gram-negative bacterium, is the etiologic agent of tularemia and has
recently been classified as a category A bioterrorism agent. Infections with F. tularensis …

Francisella tularensis, a gram-negative, facultative, intracellular bacterium, is the etiologic
agent of tularemia and a category A bioterrorism agent. Little is known about the mechanism …

Francisella tularensis, an aerobic, non-spore-forming, gram-negative coccobacillus, is the
causative agent of tularemia. We reported previously that F. tularensis live vaccine strain …

Francisella tularensis, the causative agent of tularemia, is a gram-negative facultative
intracellular bacterium. Toll-like receptor (TLR) 4 is considered to be critical for inducing host …

The means by which Francisella tularensis, the causative agent of tularemia, are recognized
by mammalian immune systems are poorly understood. Here we wished to explore the …

Immunization with Ft-LPS provokes an antigen-specific, B-1a cell-derived antibody response
that protects WT mice against an otherwise lethal challenge with Ft LVS. However, this same …

Francisella tularensis (Ft), the causative agent of tularemia, elicits a potent inflammatory
response early in infection, yet persists within host macrophages and can be lethal if left …

The role (s) of gamma interferon (IFN-gamma), tumor necrosis factor alpha (TNF-alpha), and
interleukin-4 (IL-4) in establishment and maintenance of protective immunity to Francisella …

Abstract Francisella tularensis (Ft), a Gram-negative intracellular bacterium, is the etiologic
agent of tularemia. Although attenuated for humans, ip infection of mice with< 10 Ft live …