Biomarkers of cardiovascular disease: molecular basis and practical considerations

RS Vasan - Circulation, 2006 - Am Heart Assoc
echocardiogram) may be expected to facilitate the identification of patients with chest pain of
an ischemic etiology (angina). In a patient presenting to the emergency department with …

Cardiac biomarkers–the old and the new: a review

V Singh, P Martinezclark, M Pascual… - Coronary artery …, 2010 - journals.lww.com
Biomarkers are biological parameters that can be objectively measured and quantified as
indicators of normal biologic processes, pathogenic processes, or responses to a …

Biomarkers in acute myocardial infarction: current perspectives

S Aydin, K Ugur, S Aydin, İ Sahin… - Vascular health and risk …, 2019 - Taylor & Francis
Purpose Acute myocardial infarction (AMI) is the most common cause of death in the world.
Comprehensive risk assessment of patients presenting with chest pain and eliminating …

Benchmarks for the assessment of novel cardiovascular biomarkers

DA Morrow, JA de Lemos - Circulation, 2007 - Am Heart Assoc
The investigation of novel circulating serum and plasma biomarkers in patients with
cardiovascular disease has been accelerating at a remarkable pace. For example, a …

Evaluating the clinical utility of a biomarker: a review of methods for estimating health impact

MJ Pletcher, M Pignone - Circulation, 2011 - Am Heart Assoc
Biomarkers, broadly defined, are markers of a biological process or state. 1 Biomarkers are
often used in research studies, but they may also be useful for clinicians and patients if they …

Advances in cardiovascular biomarker discovery

CM Ghantous, L Kamareddine, R Farhat, FA Zouein… - Biomedicines, 2020 - mdpi.com
Cardiovascular diseases are the leading causes of mortality worldwide. Among them,
hypertension and its pathological complications pose a major risk for the development of …

Identifying novel biomarkers for cardiovascular disease risk prediction

Y Ge, TJ Wang - Journal of internal medicine, 2012 - Wiley Online Library
The primary prevention of cardiovascular disease relies on the ability to identify at‐risk
individuals long before the development of overt events. In the past decade, research into …

How-to guide on biomarkers: biomarker definitions, validation and applications with examples from cardiovascular disease

VO Puntmann - Postgraduate medical journal, 2009 - academic.oup.com
A biomarker is a characteristic that can be objectively measured and evaluated as an
indicator of normal biological processes, pathogenic processes or pharmacological …

Vascular biomarkers and surrogates in cardiovascular disease

JC Tardif, T Heinonen, D Orloff, P Libby - Circulation, 2006 - Am Heart Assoc
Cardiovascular biomarker research efforts have resulted in the identification of new risk
factors and novel drug targets, as well as the establishment of treatment guidelines …

The search for a biomarker of cardiac ischemia

DA Morrow, JA de Lemos, MS Sabatine… - Clinical …, 2003 - academic.oup.com
With 8 million patients arriving with nontraumatic chest pain to emergency departments in
the US each year, the clinical evaluation, triage, and management of patients with possible …