Pretreatment of nafithromycin attenuates inflammatory response in murine lipopolysaccharide induced acute lung injury

J Trivedi, J Shaikh, N Chavan, D Thorve, B Chaudhary… - Cytokine, 2020 - Elsevier
Acute respiratory distress syndrome following an acute lung injury (ALI) is a life threatening
inflammatory condition predominantly characterized by vascular protein leakage, neutrophil …

Anti-inflammatory activity of azithromycin attenuates the effects of lipopolysaccharide administration in mice

VI Tkalčević, B Bošnjak, B Hrvačić, M Bosnar… - European journal of …, 2006 - Elsevier
Macrolide antibacterials inhibit the production of various cytokines and the migration of
inflammatory cells. These anti-inflammatory actions of macrolides may be beneficial in …

Effect of Clarithromycin on Lung Inflammation and Alveolar Macrophage Function in Klebsiella pneumoniae B5055-Induced Acute Lung Infection in BALB/c mice

V Kumar, K Harjai, S Chhibber - Journal of Chemotherapy, 2008 - Taylor & Francis
Acute lung injuries due to acute lung infections remain the major cause of mortality. Thus
antibiotics with immunomodulatory and anti-inflammatory activities, regard-less of their …

Comparing the protective effects of ciprofloxacin, moxifloxacin and levofloxacin in mice with lipopolysaccharide‐induced acute lung injuries

HC HUANG, CC SHIEH, WL YU, KC CHENG… - …, 2008 - Wiley Online Library
Background and objective: Ciprofloxacin, moxifloxacin and levofloxacin are recognized
immunomodulators. Their effects in acute lung injuries have not been tested. This study …

Azithromycin and clarithromycin inhibit lipopolysaccharide-induced murine pulmonary neutrophilia mainly through effects on macrophage-derived granulocyte …

M Bosnar, B Bošnjak, S Čužić, B Hrvačić… - Journal of pharmacology …, 2009 - ASPET
Macrolide antibiotics possess immunomodulatory/anti-inflammatory properties. These
properties are considered fundamental for the efficacy of macrolide antibiotics in the …

[HTML][HTML] Anti-inflammatory effects of clarithromycin in ventilator-induced lung injury

L Amado-Rodríguez, A González-López… - Respiratory …, 2013 - Springer
Background Mechanical ventilation can promote lung injury by triggering a pro-inflammatory
response. Macrolides may exert some immunomodulatory effects and have shown …

The anti-inflammatory activity of clarithromycin inhibits TNFa production and prolongs survival following lipopolysaccharide administration in mice

V Ivetić Tkalčević, B Bošnjak, I Pašalić, B Hrvačić… - International journal of …, 2008 - croris.hr
Sažetak Macrolide antibiotics, well known for their antimicrobial properties, also possess a
range of anti-inflammatory and immunomodulatory properties. They were shown to be …

[HTML][HTML] Effects of glycyrrhizin on lipopolysaccharide-induced acute lung injury in a mouse model

S Am Lee, SH Lee, JY Kim, WS Lee - Journal of Thoracic Disease, 2019 - ncbi.nlm.nih.gov
Background Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are
serious clinical disease entities characterized by inflammatory pulmonary edema, which …

Levonadifloxacin, a novel benzoquinolizine fluoroquinolone, modulates lipopolysaccharide-induced inflammatory responses in human whole-blood assay and murine …

A Patel, GV Sangle, J Trivedi… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
Fluoroquinolones are reported to possess immunomodulatory activity; hence, a novel
benzoquinolizine fluoroquinolone, levonadifloxacin, was evaluated in lipopolysaccharide …

Isoforskolin pretreatment attenuates lipopolysaccharide-induced acute lung injury in animal models

W Yang, D Qiang, M Zhang, L Ma, Y Zhang… - International …, 2011 - Elsevier
Isoforskolin was isolated from Coleus forskohlii native to Yunnan in China. We hypothesize
that isoforskolin pretreatment attenuates processes of acute lung injury induced by …