The disaccharide trehalose is widely distributed in nature and can serve as a carbon
reservoir, a signaling molecule for controlling glucose metabolism and a stress protectant …

Trehalose accumulates dramatically in microorganisms during heat shock and osmotic
stress and helps protect cells against thermal injury and oxygen radicals. Here we …

Trehalose is an endogenously synthesized disaccharide that is broadly distributed in the
biosphere. While recognized for its carbohydrate reserve and metabolic regulatory functions …

Trehalose is a ubiquitous molecule that occurs in lower and higher life forms but not in
mammals. Till about 40 years ago, trehalose was visualized as a storage molecule, aiding …

Desiccation is a common stress that bacteria face in the natural environment, and thus, they
have developed a variety of protective mechanisms to mitigate the damage caused by water …

The disaccharide trehalose is produced in large quantities by diverse organisms during a
variety of stresses. Trehalose prevents proteins from denaturing at high temperatures in …

Endogenously synthesized trehalose is a stress protectant in Escherichia coli. Externally
supplied trehalose does not serve as a stress protectant, but it can be utilized as the sole …

Trehalose is a nonreducing disaccharide in which the two glucose units are linked in an α, α-
1, 1-glycosidic linkage. This sugar is present in a wide variety of organisms, including …

Trehalose transport and metabolism in Escherichia coli are induced by trehalose in the
growth medium but only at low osmolarity. In contrast, synthesis of internal trehalose as an …

The biosynthesis of trehalose has been previously shown to serve as an important
osmoprotectant and stress protectant in Escherichia coli. Our results indicate that …