The Oct‐4 transcription factor, a member of the POU family that is also known as Oct‐3 and
Oct3/4, is expressed in totipotent embryonic stem cells (ES) and germ cells, and it has a …

The octamer-binding transcription factor 4 gene encodes a nuclear protein (Oct4, also
known as Pou5F1 and Oct3/4) that belongs to a family of transcription factors containing the …

Octamer-binding transcription factor 4 (Oct4) encodes a POU-domain transcription factor
(Scholer et al., 1990). The gene is specifically expressed in embryonic stem (ES) cells but …

The transcription factor OCT4 (officially POU5F1; alternatively OCT3, OCT3/4, OTF3, and
OTF4) is currently considered a main regulator of human embryonic stem cell pluripotency …

Since its discovery as a critical regulator of pluripotency in embryonic stem (ES) cells and
the inner cells mass of the developing blastocyst, the Pou domain-containing transcription …

The first cell differentiation event in mammalian embryogenesis segregates inner cell mass
lineage from the trophectoderm at the blastocyst stage. Oct-4, a member of the POU family of …

The Pou domain containing transcription factor Oct4 is a well-established regulator of
pluripotency in the inner cell mass of the mammalian blastocyst as well as in embryonic …

OCT-4 transcription factors play an important role in maintaining the pluripotent state of
embryonic stem cells and may prevent expression of genes activated during differentiation …

The Oct4 protein, encoded by the Pou5f1 gene was the very first master gene, discovered 25
years ago, to be absolutely required for the stemness properties of murine and primate …

The POU domain transcription factor OCT4 is a key regulator of pluripotency in the early
mammalian embryo and is highly expressed in the inner cell mass of the blastocyst …