[HTML][HTML] Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection
T-cell immunity is important for recovery from COVID-19 and provides heightened immunity
for re-infection. However, little is known about the SARS-CoV-2-specific T-cell immunity in …
for re-infection. However, little is known about the SARS-CoV-2-specific T-cell immunity in …
[HTML][HTML] The importance of measuring SARS-CoV-2-specific T-cell responses in an ongoing pandemic
Neutralizing antibodies are considered a correlate of protection against SARS-CoV-2
infection and severe COVID-19, although they are not the only contributing factor to …
infection and severe COVID-19, although they are not the only contributing factor to …
[HTML][HTML] SARS-CoV-2-specific T cells exhibit phenotypic features of helper function, lack of terminal differentiation, and high proliferation potential
Summary Convalescing coronavirus disease 2019 (COVID-19) patients mount robust T cell
responses against SARS-CoV-2, suggesting an important role of T cells in viral clearance …
responses against SARS-CoV-2, suggesting an important role of T cells in viral clearance …
Identification of SARS-CoV-2 nucleocapsid and spike T-cell epitopes for assessing T-cell immunity
Developing optimal T-cell response assays to severe acute respiratory syndrome
coronavirus type 2 (SARS-CoV-2) is critical for measuring the duration of immunity to this …
coronavirus type 2 (SARS-CoV-2) is critical for measuring the duration of immunity to this …
[HTML][HTML] COVID-19 and the Path to Immunity
DS Stephens, MJ McElrath - Jama, 2020 - jamanetwork.com
The emergence of adaptive immunity in response to the novel Betacoronavirus, severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), occurs within the first 7 to 10 days …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), occurs within the first 7 to 10 days …
[HTML][HTML] Imbalance of regulatory and cytotoxic SARS-CoV-2-reactive CD4+ T cells in COVID-19
The contribution of CD4+ T cells to protective or pathogenic immune responses to SARS-
CoV-2 infection remains unknown. Here, we present single-cell transcriptomic analysis of> …
CoV-2 infection remains unknown. Here, we present single-cell transcriptomic analysis of> …
[HTML][HTML] Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2
L Swadling, MO Diniz, NM Schmidt, OE Amin… - Nature, 2022 - nature.com
Individuals with potential exposure to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) do not necessarily develop PCR or antibody positivity, suggesting that some …
(SARS-CoV-2) do not necessarily develop PCR or antibody positivity, suggesting that some …
[HTML][HTML] A third vaccination with a single T cell epitope confers protection in a murine model of SARS-CoV-2 infection
IN Pardieck, TC van der Sluis… - Nature …, 2022 - nature.com
Understanding the mechanisms and impact of booster vaccinations are essential in the
design and delivery of vaccination programs. Here we show that a three dose regimen of a …
design and delivery of vaccination programs. Here we show that a three dose regimen of a …
[HTML][HTML] Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms
We describe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell
responses, soluble markers of inflammation, and antibody levels and neutralization capacity …
responses, soluble markers of inflammation, and antibody levels and neutralization capacity …
SARS-CoV-2–specific T cells are rapidly expanded for therapeutic use and target conserved regions of the membrane protein
MD Keller, KM Harris… - Blood, The Journal …, 2020 - ashpublications.org
T-cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have
been described in recovered patients, and may be important for immunity following infection …
been described in recovered patients, and may be important for immunity following infection …