Physiological and lifestyle-related cardiovascular risk factors for vessels, ventricle, and valve

P Sarajlic - 2024 - openarchive.ki.se
Cardiovascular diseases are the most common cause of mortality globally, claiming twice as
many lives as cancer and more than all nutritional disorders, infectious diseases, and …

Physical activity does not reduce aortic valve stenosis incidence

P Sarajlic, A Wolk, M Bäck, SC Larsson - Circulation Journal, 2018 - jstage.jst.go.jp
Background: Physical activity is associated with lower risk of coronary and cerebrovascular
disease but its potential role in prevention of aortic valve stenosis (AVS) is unclear. Methods …

Observational and genetic associations of modifiable risk factors with aortic valve stenosis: a prospective cohort study of 0.5 million participants

N Huang, Z Zhuang, Z Liu, T Huang - Nutrients, 2022 - mdpi.com
Background: Observational studies have shown that modifiable risk factors are associated
with aortic valve stenosis (AVS). However, the causality behind these associations remains …

Atherosclerosis associated pathways are upregulated in stenotic aortic valves from patients with severe concomitant coronary artery disease

O Plunde, P Sarajlic, A Franco-Cereceda… - European Heart …, 2021 - academic.oup.com
Aortic valve stenosis (AVS) share pathobiology and risk factors with atherosclerosis.
However, medical treatment effective against atherosclerosis lack ability to halt the …

The effects of exercise on cardiovascular disease risk factors and cardiovascular physiology in rheumatoid arthritis

GS Metsios, RH Moe, M Van Der Esch… - Rheumatology …, 2020 - Springer
Cardiovascular disease (CVD) morbidity and mortality is highly prevalent in patients with
rheumatoid arthritis (RA) with debilitating effects for the individual as well as significant …

Physical inactivity and arterial dysfunction in patients with rheumatoid arthritis

MA Crilly, A Wallace - Scandinavian journal of rheumatology, 2013 - Taylor & Francis
Objectives: The increased risk of cardiovascular (CV) disease associated with rheumatoid
arthritis (RA) is partly attributable to chronic inflammation, but traditional CV risk factors such …

Transcriptomic Analysis Reveals Sex Differences in Gene Expression Profiling of Stenotic Aortic Valves

E Le Nezet, M Voisine, R Tam, Z LI, N Gaudreault… - Circulation, 2023 - Am Heart Assoc
Introduction: In aortic stenosis (AS), women present less aortic valve calcification and more
aortic valve fibrosis than men for the same hemodynamic severity. However, the specific …

Risk score for coronary heart disease (CHD-RISK) and hemodynamically significant aortic valve stenosis

O Christopher, Z Xiong, Y Huang, X Zhuang… - Nutrition, Metabolism …, 2023 - Elsevier
Background and aim Multiple studies have investigated the association between coronary
heart disease (CHD) risk factors and aortic valve stenosis (AS). However, limited studies …

Deep Learning-Based GWAS of Aortic Valve Function Links 81 Loci to Aortic Stenosis Risk

J Pirruccello, S Kany, J Ramo, C Hou, SJ Jurgens… - Circulation, 2023 - Am Heart Assoc
Background & Aims: The genetic influences on normal aortic valve (AV) function and their
impact on aortic stenosis (AS) risk are of significant interest. We sought to identify common …

Association of physical inactivity with increased cardiovascular risk in patients with rheumatoid arthritis

GS Metsios, A Stavropoulos-Kalinoglou… - European Journal of …, 2009 - academic.oup.com
Objective Patients with rheumatoid arthritis (RA) are characterized by reduced physical
activity and increased morbidity and mortality from cardiovascular disease (CVD). The aim of …