[HTML][HTML] Eriocalyxin B induces apoptosis and autophagy involving Akt/mammalian target of rapamycin (mTOR) pathway in prostate cancer cells

Z Yu, Y Chen, C Liang - Medical Science Monitor: International …, 2019 - ncbi.nlm.nih.gov
Background Eriocalyxin B (EriB), a diterpenoid isolated from the plant Isodon eriocalyx, has
been shown to possess anti-tumor properties. However, few systematic studies of the …

Eriocalyxin B biological activity: a review on its mechanism of action

A Riaz, B Saleem, G Hussain, I Sarfraz… - Natural Product …, 2019 - journals.sagepub.com
Natural products, a rich source of bioactive chemical compounds, have served humans as a
safer drug of choice since times. Eriocalyxin B, an ent-Kaurene diterpenoid, has been …

Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase-and p53-dependent pathways

L Li, GGL Yue, CBS Lau, H Sun, KP Fung… - Toxicology and applied …, 2012 - Elsevier
Pancreatic cancer is difficult to detect early and responds poorly to chemotherapy. A
breakthrough in the development of new therapeutic agents is urgently needed. Eriocalyxin …

Eriocalyxin B inhibits proliferation and induces apoptosis through down-regulation of Bcl-2 and activation of caspase-3 in human bladder cancer cells

A Rasul, J Liu, Y Liu, FM Millimouno… - ||| Bangladesh …, 2013 - bdpsjournal.org
Eriocalyxin B (EriB) has been shown to possess promising anti-cancer potential against
various cancer cells. However, its effect against bladder cancer cells remained unexplored …

Eriocalyxin B, a novel autophagy inducer, exerts anti-tumor activity through the suppression of Akt/mTOR/p70S6K signaling pathway in breast cancer

X Zhou, GGL Yue, AML Chan, SKW Tsui… - Biochemical …, 2017 - Elsevier
Eriocalyxin B (EriB), a natural ent-kaurane diterpenoid presented in the plant Isodon
eriocalyx var. laxiflora, has been reported to diminish angiogenesis-dependent breast tumor …

[HTML][HTML] Eriocalyxin B induces apoptosis in lymphoma cells through multiple cellular signaling pathways

YW Zhang, XX Jiang, QS Chen, WY Shi, L Wang… - Experimental …, 2010 - Elsevier
OBJECTIVE: Eriocalyxin B (EriB) is a natural diterpenoid purified from Isodon eriocalyx var.
laxiflora and possesses strong antileukemic activity. In this study, we further investigated its …

[PDF][PDF] Eriocalyxin B induces apoptosis in human triple negative breast cancer cells via inhibiting STAT3 activation and mitochondrial dysfunction

A Riaz, A Rasul, G Hussain, M Zubair, K Samiullah… - Pak J Pharm …, 2019 - academia.edu
Eriocalyxin B (EriB), a potent ent-kaurene extracted from Isodon eriocalyx, has turned up as
novel anti-cancer agent during recent years against a range of cancer types. TNBC (Triple …

Isodon eriocalyx and its bioactive component Eriocalyxin B enhance cytotoxic and apoptotic effects of gemcitabine in pancreatic cancer

L Li, SL Zhao, GGL Yue, TP Wong, JX Pu, HD Sun… - Phytomedicine, 2018 - Elsevier
Background Pancreatic cancer, associated with poor prognosis and low survival rate, has
been the fourth leading cause of cancer-related death in the US. Although gemcitabine …

Epieriocalyxin A induces cell apoptosis through JNK and ERK1/2 signaling pathways in colon cancer cells

Z Wang, Z Xu, Z Niu, B Liang, J Niu - Cell biochemistry and biophysics, 2015 - Springer
Colorectal cancer is one of the most commonly diagnosed cancers in the world. Currently,
drug resistance of cancer cell to chemotherapy is a major cause for cancer recurrence and …

Eriocalyxin B blocks human SW1116 colon cancer cell proliferation, migration, invasion, cell cycle progression and angiogenesis via the JAK2/STAT3 signaling …

YM Lu, W Chen, JS Zhu… - Molecular medicine …, 2016 - spandidos-publications.com
Eriocalyxin B, a natural ent-kaurene diterpene compound, has been shown to prevent
carcinogenesis and tumor development. However, little is known regarding the mechanism …