Since the discovery of nuclear factor-kappa B (NF-κB) in 1986, many studies have been
conducted showing the link between the NF-κB signalling pathway and control of the …

The role of nuclear factor (NF)-κB in the regulation of apoptosis in normal and cancer cells
has been extensively studied in recent years. Constitutive NF-κB activity in B lymphocytes as …

Recent progress in the identification and functional analysis of protein kinases and adapter
molecules that lead to activation of NF-κB family transcription factors has lead to a quite …

NF-κB/Rel transcription factors have recently emerged as crucial regulators of cell survival.
Activation of NF-κB antagonizes programmed cell death (PCD) induced by tumor necrosis …

Apoptosis is a mode of cell death that plays an important role in both pathological and
physiological processes. Research during the last decade has delineated the entire …

It is not clear why on treatment with certain killer cytokines or chemotherapeutic agents,
some cells undergo apoptosis while others do not. The delineation of sensitivity/resistance …

NF-κB/Rel transcription factors block apoptosis or programmed cell death (PCD) induced by
tumor necrosis factor (TNF) α. The antiapoptotic activity of NF-κB is alsocrucial for immunity …

The process of apoptosis is used to eliminate unwanted cells from a wide variety of
organisms. Various extracellular signals, often converging in common intracellular …

NF-κB is a transcription factor of eukaryote, five members of whose family in mammals and
three in drosophila. Transcription factors of the NF-κB family are activated in response to …

The activation of NF-κB inhibits apoptosis via a mechanism involving upregulation of various
antiapoptotic genes, such as cellular FLICE-inhibitory protein (c-FLIP), Bcl-x L, A1/Bfl-1, and …