Dual effect of curcumin in preventing atherosclerosis: the potential role of pro-oxidant–antioxidant mechanisms

A Sahebkar - Natural product research, 2015 - Taylor & Francis
Dear Editor, Curcumin is a polyphenolic compound with a multitude of beneficial actions for
cardiometabolic health. The protective effects of chronic supplementation with curcumin …

Cardiovascular protection by curcumin: molecular aspects

G Kapakos, V Youreva, AK Srivastava - 2012 - nopr.niscpr.res.in
Curcumin is the active component in turmeric—a spice that has been extensively used as a
culinary agent and a home remedy to prevent and treat many diseases in India and other …

[HTML][HTML] Curcumin-the nutraceutical with pleiotropic effects? Which cardiometabolic subjects might benefit the most?

S Surma, A Sahebkar, J Urbański, PE Penson… - Frontiers in …, 2022 - frontiersin.org
Despite continuous advances in pharmacotherapy, atherosclerotic cardiovascular disease
remains the world's leading killer. Atherosclerosis relates not only to an increased level of …

[HTML][HTML] Curcumin as a natural remedy for atherosclerosis: a pharmacological review

L Singh, S Sharma, S Xu, D Tewari, J Fang - Molecules, 2021 - mdpi.com
Curcumin, a natural polyphenolic compound present in Curcuma longa L. rhizomes, shows
potent antioxidant, anti-inflammatory, anti-cancer, and anti-atherosclerotic properties …

[HTML][HTML] Protective effects of curcumin in cardiovascular diseases—Impact on oxidative stress and mitochondria

FF Cox, A Misiou, A Vierkant, N Ale-Agha, M Grandoch… - Cells, 2022 - mdpi.com
Cardiovascular diseases (CVDs) contribute to a large part of worldwide mortality. Similarly,
two of the major risk factors for these diseases, aging and obesity, are also global problems …

Why it is necessary to translate curcumin into clinical practice for the prevention and treatment of metabolic syndrome?

A Sahebkar - Biofactors, 2013 - Wiley Online Library
Curcumin (diferuloylmethane) is the yellow‐orange pigment of dried Curcuma longa L.
rhizomes (turmeric). During the past two decades, there has been a large volume of …

Modulatory effects of curcumin on the atherogenic activities of inflammatory monocytes: Evidence from in vitro and animal models of human atherosclerosis

S Mohammadian Haftcheshmeh, MR Karimzadeh… - Biofactors, 2020 - Wiley Online Library
Atherosclerosis is a complex and long‐lasting disorder characterized by chronic
inflammation of arteries that leads to the initiation and progression of lipid‐rich plaques, in …

A systematic review and meta-analysis of randomized controlled trials investigating the effects of curcumin on blood lipid levels

A Sahebkar - Clinical Nutrition, 2014 - Elsevier
Background & aims Curcumin is a polyphenolic natural compound with diverse and
attractive biological activities. There has been in-vitro, preclinical and clinical evidence on …

Protective effects of curcumin on endothelium: An updated review

M Alidadi, L Liberale, F Montecucco, M Majeed… - Studies on Biomarkers …, 2021 - Springer
Endothelial dysfunction is the common early stage of most cardiovascular afflictions. The
endothelium is considered the main mediator of vascular homeostasis via its vasodilator …

[HTML][HTML] The effect of curcumin on some of traditional and non-traditional cardiovascular risk factors: a pilot randomized, double-blind, placebo-controlled trial

P Mirzabeigi, AH Mohammadpour… - Iranian journal of …, 2015 - ncbi.nlm.nih.gov
Numerous interventional studies in clinical and preclinical setting stated that intake of
curcumin may provide protection against cardiovascular disease. The aim of this trial was …