Advances in gene therapy have been foreshadowing its potential for the treatment of a vast
range of diseases involving genetic malfunctioning. However, its therapeutic efficiency and …

Silica-based nanoparticles are promising carriers for gene delivery applications. To gain
insights into the effect of particle size on gene transfection efficiency, amine-modified …

The application of nanotechnology to biomedical research is expected to have a major
impact leading to the development of new types of diagnostic and therapeutic tools. One …

We have known for a while that silica is a promising candidate gene delivery vector. New in
vivo data from Dhruba Bharali and co-workers raise the hopes a notch for such approaches …

Gene therapy has attracted much attention in modern society and provides a promising
approach for treating genetic disorders, diseases and cancers. Safe and effective vectors …

The transport of nucleic acid-based reagents is predicated upon developing structurally
stable delivery systems that can preferentially bind and protect DNA and RNA, and release …

Silica is a promising carrier material for nanoparticle-facilitated drug delivery, gene therapy,
and molecular imaging. Understanding of their pharmacokinetics is important to resolve …

Silica nanoparticles are attractive candidates for the development of safe and efficient non-
viral gene carriers, owing to their controlled morphologies, potential of facile surface …

Colloidal carriers based on silica (Si) matrices are an innovative approach within the context
of therapeutic drug delivery systems. These carriers are emerging as a great promise for …

The administration of cytotoxic drugs in classical chemotherapy is frequently limited by water
solubility, low plasmatic stability, and a myriad of secondary effects associated with their …