Advances in the immunobiology of eosinophils and their role in disease

GM Walsh - Critical reviews in clinical laboratory sciences, 1999 - Taylor & Francis
Eosinophils play a protective role in host immunity to infections by parasitic worms and,
detrimentally, are involved in the pathophysiology of asthma and other allergic diseases …

Eosinophils: changing perspectives in health and disease

HF Rosenberg, KD Dyer, PS Foster - Nature Reviews Immunology, 2013 - nature.com
Eosinophils have been traditionally perceived as terminally differentiated cytotoxic effector
cells. Recent studies have profoundly altered this simplistic view of eosinophils and their …

[HTML][HTML] Eosinophils and eosinophilic immune dysfunction in health and disease

DJ Jackson, P Akuthota… - European Respiratory …, 2022 - Eur Respiratory Soc
The functions ascribed to eosinophils have classically been limited to host defence against
certain parasitic infections and potentially deleterious effects in the setting of specific …

Eosinophils: multifaceted biological properties and roles in health and disease

H Kita - Immunological reviews, 2011 - Wiley Online Library
Eosinophils are leukocytes resident in mucosal tissues. During T‐helper 2 (Th2)‐type
inflammation, eosinophils are recruited from bone marrow and blood to the sites of immune …

The role and immunobiology of eosinophils in the respiratory system: a comprehensive review

SS Eng, ML DeFelice - Clinical reviews in allergy & immunology, 2016 - Springer
The eosinophil is a fully delineated granulocyte that disseminates throughout the
bloodstream to end-organs after complete maturation in the bone marrow. While the …

[引用][C] The eosinophil: new insights into its function in human health and disease

A Wardlaw - The Journal of pathology, 1996 - Wiley Online Library
Although the eosinophil was first identified over a century ago and its association with
asthma and parasitic disease was noted shortly afterwards, its role has remained enigmatic …

Contributions of eosinophils to human health and disease

AD Klion, SJ Ackerman… - Annual Review of …, 2020 - annualreviews.org
The human eosinophil has long been thought to favorably influence innate mucosal
immunity but at times has also been incriminated in disease pathophysiology. Research into …

Biology of eosinophils

H Kita, BS Bochner - Middleton's allergy principles and practice, 2013 - books.google.com
The eosinophilis a bone marrow–derived, peripheral blood and tissue granulocyte
prominent in allergic and inflammatory responses against metazoan helminthic parasites but …

[HTML][HTML] Eosinophils

HF Rosenberg - Encyclopedia of Immunobiology, 2016 - ncbi.nlm.nih.gov
Eosinophils have been traditionally understood as end-stage, primarily cytotoxic effector
cells. Recent studies have had profound impact on this limited view and have led to new …

Eosinophil granule proteins and their role in disease

GM Walsh - Current opinion in hematology, 2001 - journals.lww.com
The eosinophil has a potent armory of proinflammatory mediators with considerable
potential to initiate and sustain an inflammatory response. These include cytotoxic granule …