The mouse hemisected spinal cord with attached dorsal roots and spinal ganglia in vitro
preparation was used to investigate the effects of the capsaicin antagonist, capsazepine (2 …

An action of capsaicin was investigated on dorsal root-evoked synaptic transmission to
substantia gelatinosa (SG) neurons in adult rat spinal cord slices by use of the whole-cell …

Abstract Low doses (0.2–0.8 μM) of capsaicin were used to achieve selective excitation of C-
fibres and the consequent synaptic activation of dorsal horn neurons (laminae I–VI) in the …

The acute and chronic effects of capsaicin on rat spinal dorsal horn neurons and the
excitatory transmission in the dorsal horn were investigated by means of intracellular …

1 Capsazepine has recently been described as a competitive capsaicin antagonist. We have
used this compound to test the hypotheses that the in vitro and in vivo effects of capsaicin …

Whole-cell voltage-clamp techniques were employed to investigate a capsaicin-induced
current in substantia gelatinosa (SG) neurons in the dorsal horn of adult rat spinal cord …

Actions of capsaicin were examined on synaptic transmissions in the substantia gelatinosa
(SG) of adult rat spinal cord slices using the whole-cell patch-recording technique. Bath …

The effects of capsaicin were investigated on different populations of dorsal root ganglion
cells in the in vitro mouse spinal cord-dorsal root ganglion preparation using intracellular …

We have studied the effects of capsaicin, administered at concentrations found to be
antinociceptive in behavioural tests, on nociceptive responses evoked both in spinal dorsal …

Capsaicin produces pain by selectively activating polymodal nociceptive neurons. This
involves a membrane depolarization and the opening of a unique, cation-selective, ion …