Age-related responses to a bout of mechanotherapy in skeletal muscle of rats

DW Van Pelt, AL Confides… - Journal of Applied …, 2019 - journals.physiology.org
Cyclic compressive loading (CCL) is a massage mimetic that improves muscle regrowth
from atrophy in adult rats. Therefore, we tested if a single bout of CCL increases anabolic …

Massage as a mechanotherapy promotes skeletal muscle protein and ribosomal turnover but does not mitigate muscle atrophy during disuse in adult rats

MM Lawrence, DW Van Pelt, AL Confides… - Acta …, 2020 - Wiley Online Library
Aim Interventions that decrease atrophy during disuse are desperately needed to maintain
muscle mass. We recently found that massage as a mechanotherapy can improve muscle …

Muscle from aged rats is resistant to mechanotherapy during atrophy and reloading

MM Lawrence, DW Van Pelt, AL Confides, ZR Hettinger… - Geroscience, 2021 - Springer
Massage is a viable mechanotherapy to improve protein turnover during disuse atrophy and
improve muscle regrowth during recovery from disuse atrophy in adult muscle. Therefore …

Enhanced skeletal muscle regrowth and remodelling in massaged and contralateral non‐massaged hindlimb

BF Miller, KL Hamilton, ZR Majeed… - The Journal of …, 2018 - Wiley Online Library
Key points Muscle fibre cross sectional area is enhanced with massage in the form of cyclic
compressive loading during regrowth after atrophy. Massage enhances protein synthesis of …

Exercise‐induced muscle growth is muscle‐specific and age‐dependent

JRS Leiter, J Peeler, JE Anderson - Muscle & nerve, 2011 - Wiley Online Library
Introduction: Sarcopenia, and the importance of satellite cells (SCs) in muscle growth led us
to examine the effects of exercise and age on SC activation and gene expression. Methods …

Aging-sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophy

F Haddad, GR Adams - Journal of Applied Physiology, 2006 - journals.physiology.org
Sarcopenia is an age-related loss of muscle mass and strength. The aged can increase
various measures of muscle size and strength in response to resistance exercise (RE), but …

Massage as a mechanotherapy for skeletal muscle

DW Van Pelt, MM Lawrence, BF Miller… - Exercise and sport …, 2021 - journals.lww.com
Massage is anecdotally associated with many health benefits, but physiological and
clinically relevant mechanisms recently have begun to be investigated in a controlled …

Age-related susceptibility to muscle damage following mechanotherapy in rats recovering from disuse atrophy

ZR Hettinger, K Hamagata, AL Confides… - The Journals of …, 2021 - academic.oup.com
The inability to fully recover lost muscle mass following periods of disuse atrophy
predisposes older adults to lost independence and poor quality of life. We have previously …

Reduced frequency of resistance-type exercise training promotes adaptation of the aged skeletal muscle microenvironment

MA Naimo, EP Rader, J Ensey… - Journal of Applied …, 2019 - journals.physiology.org
The purpose of this study was to characterize the growth and remodeling molecular
signaling response in aged skeletal muscle following 1 mo of “resistance-type exercise” …

Overexpression of HSP10 in skeletal muscle of transgenic mice prevents the age-related fall in maximum tetanic force generation and muscle Cross-Sectional Area

AC Kayani, GL Close, WH Dillmann… - American Journal …, 2010 - journals.physiology.org
Skeletal muscle atrophy and weakness are major contributors to frailty and impact
significantly on quality of life of older people. Muscle aging is characterized by a loss of …