Activator of metastasis in cancer cells, Mst1/S100A4 protein binds to tumor suppressor protein p53
M Grigorian, E Lukanidin - Genetika, 2003 - europepmc.org
This study for the first time demonstrates a physical and functional interaction between the
Ca (2+)-binding protein Mts1/S100A4 and tumor suppressor p53 protein. Using different in …
Ca (2+)-binding protein Mts1/S100A4 and tumor suppressor p53 protein. Using different in …
[HTML][HTML] Heterocomplex formation between metastasis-related protein S100A4 (Mts1) and S100A1 as revealed by the yeast two-hybrid system
S100A4 (Mts1) is a Ca2+-binding protein of the S100 family. This protein plays an important
role in promoting tumor metastasis. In order to identify S100A4 interacting proteins, we have …
role in promoting tumor metastasis. In order to identify S100A4 interacting proteins, we have …
Key promoter elements involved in transcriptional activation of the cancer-related gene coding for S100P calcium-binding protein
A Gibadulinova, I Oveckova, S Parkkila… - Oncology …, 2008 - spandidos-publications.com
S100P gene encodes a calcium-binding protein expressed in different tumor tissues and is
functionally implicated in malignant phenotype. Despite consistent relationship to cancer …
functionally implicated in malignant phenotype. Despite consistent relationship to cancer …
Tissue-Specific Posttranscriptional Downregulation of Expression of the S100A4(mts1) Gene in Transgenic Animals
N Ambartsumian, J Klingelhöfer, M Grigorian… - Invasion and …, 1999 - karger.com
Abstract The S100A4 (mts1) is a gene associated with generation of metastatic disease. In
order to analyze the consequences of alteration of the pattern of expression of the S100A4 …
order to analyze the consequences of alteration of the pattern of expression of the S100A4 …
Induction of 18A2/mts1 Gene Expression and Its Effects on Metastasis and Cell Cycle Control
C Parker, PA Whittaker, BA Usmani… - DNA and cell …, 1994 - liebertpub.com
The metastasis associated 18A2/mts1 gene was inserted into the mammalian expression
vector pMAM neo placing it under the control of the dexamethasone-inducible MMTV …
vector pMAM neo placing it under the control of the dexamethasone-inducible MMTV …
[HTML][HTML] Binding of two nuclear complexes to a novel regulatory element within the human S100A9 promoter drives the S100A9 gene expression
C Kerkhoff, HA Hofmann, J Vormoor… - Journal of Biological …, 2002 - ASBMB
S100A9, also referred to as MRP14, is a calcium-binding protein whose expression is tightly
regulated during differentiation of myeloid cells. The present study was performed to study …
regulated during differentiation of myeloid cells. The present study was performed to study …
The metastasis-associated Mts1 (S100A4) protein could act as an angiogenic factor
N Ambartsumian, JÈ KlingelhoÈfer, M Grigorian… - Oncogene, 2001 - nature.com
The involvement of Mts1 (S100A4), a small Ca 2+-binding protein in tumor progression and
metastasis had been demonstrated. However, the mechanism by which mts1 (S100A4) …
metastasis had been demonstrated. However, the mechanism by which mts1 (S100A4) …
[HTML][HTML] A κB-related binding site is an integral part of the mts1 gene composite enhancer element located in the first intron of the gene
E Tulchinsky, E Prokhortchouk, G Georgiev… - Journal of Biological …, 1997 - ASBMB
The transcription of the mts1 gene correlates with the metastatic potential of mouse
adenocarcinomas. Here we describe strong enhancer whose location coincides with the …
adenocarcinomas. Here we describe strong enhancer whose location coincides with the …
Expression of antisense RNA to S100A4 gene encoding an S100-related calcium-binding protein suppresses metastatic potential of high-metastatic Lewis lung …
K Takenaga, Y Nakamura, S Sakiyama - Oncogene, 1997 - nature.com
S100A4 (also known as pEL98/mts1/p9Ka/18A2/42A/calvasculin/FSP1/CAPL), a member of
S100-related calcium-binding proteins, has been implicated to play a role in metastasis. In …
S100-related calcium-binding proteins, has been implicated to play a role in metastasis. In …
Metastasis-Related mts 1 Gene
EM Lukanidin, GP Georgiev - Attempts to Understand Metastasis …, 1996 - Springer
Metastasis is a multistep process involving detachment of cells from the primary tumor,
invasion and penetration of the basement membranes of blood vessels, survival in the blood …
invasion and penetration of the basement membranes of blood vessels, survival in the blood …