SMAD 8 binding to mice Msx1 basal promoter is required for transcriptional activation

R Binato, CE Alvarez Martinez, L Pizzatti… - Biochemical …, 2006 - portlandpress.com
The Msx1 gene in mice has been proven to be induced by BMP (bone morphogenetic
protein) proteins, and three binding sites for SMAD, an intracellular BMP signalling …

Hypomethylation of the metastasis-associated S100A4 gene correlates with gene activation in human colon adenocarcinoma cell lines

N Nakamura, K Takenaga - Clinical & experimental metastasis, 1998 - Springer
The DNA methylation status of the metastasis-associated S100A4 gene in S100A4-positive
and-negative human colon adenocarcinoma cell lines was examined. Northern and Western …

Metastasis promoter S100A4 is a potentially valuable molecular target for cancer therapy

GV Sherbet - Cancer letters, 2009 - Elsevier
The growth, invasion and metastatic spread of cancer have been identified with the
deregulation of cell proliferation, altered intercellular and cell-substratum adhesion and …

Expression of the metastasis‐associated mts1 gene during mouse development

J Klingelhöfer, NS Ambartsumian… - … Dynamics: An Official …, 1997 - Wiley Online Library
The mts1 gene, a member of the S100 family, is specifically expressed in different metastatic
tumor cell lines. After transfection in some nonmetastatic cell lines Mts1 can induce a …

Suppression of metastasis-associated S100A4 gene expression by gamma-interferon in human colon adenocarcinoma cells

K Takenaga - British journal of cancer, 1999 - nature.com
S100A4 belongs to the S100 subfamily of calcium-binding proteins and has been suggested
to be directly involved in invasion and metastasis of rodent and human tumour cells. The …

Inhibition of p53 transcriptional activity by the S100B calcium-binding protein

J Lin, M Blake, C Tang, D Zimmer, RR Rustandi… - Journal of Biological …, 2001 - ASBMB
The levels of S100 Ca 2+-binding proteins correlate with the progression of certain tumors,
but their role, if any, in carcinogenesis is still poorly understood. S100B protein associates …

Binding and functional characteristics of two E‐box motifs within the S100A6 (calcyclin) gene promoter

W Leśniak, J Kuźnicki - Journal of cellular biochemistry, 2006 - Wiley Online Library
Abstract S100A6 (calcyclin) is a small calcium‐binding protein of the S100 family often
associated with cancer and metastasis. We have previously shown that the E‐box sequence …

Use of DNA transfer in the induction of metastasis in experimental mammary systems.

R Barraclough, HJ Chen, BR Davies… - Biochemical Society …, 1998 - europepmc.org
The metastatic spread of cancer is a little understood process, in part because it is difficult to
model the entire process using experimental approaches in vitro. The ability to transfer DNA …

[HTML][HTML] S100A4 expression in xenograft tumors of human carcinoma cell lines is induced by the tumor microenvironment

HL Wetting, E Hadler-Olsen, S Magnussen… - The American journal of …, 2011 - Elsevier
Increased expression of the invasion-and metastasis-associated protein S100A4 is found in
many types of cancer, but the regulation of S100A4 expression is poorly understood. The …

Effect of mts1 (S100A4) expression on the progression of human breast cancer cells

M Grigorian, N Ambartsumian… - … journal of cancer, 1996 - Wiley Online Library
Abstract The mts1 (S100A4) gene, encoding a Ca2+‐binding protein of the S‐100 subfamily,
is involved in the control of tumor metastasis in some murine tumor cell lines. To further …