Using differential cDNA library screening techniques based on metastatic and nonmetastatic
rat mammary adenocarcinoma cell lines, we previously cloned and sequenced the …

We initially identified c-myc promoter binding protein 1 (MBP-1), which negatively regulates
c-myc promoter activity, from a human cervical carcinoma cell expression library …

The calcium-binding Mts1/S100A4 protein plays an important role in motility and metastatic
activity of tumor cells. Recently we showed that Mts1/S100A4 is expressed in white matter …

Abstract Small 1,000-bp fragments of genomic DNA obtained from human malignant breast
cancer cell lines when transfected into a benign rat mammary cell line enhance transcription …

Abstract S100A4, a 10–12 kDa calcium-binding protein, plays functional roles in tumor
progression and metastasis. The present study aimed to investigate the function of S100A4 …

Transgenic mice, carrying the mts1 gene, one of the genes involved in the acquisition of the
metastatic phenotype, were generated. The mts1 gene was placed under the control of the …

The melanoma cell adhesion molecule was identified as a human melanoma-associated
antigen that increases in expression as tumors increase in thickness and begin to acquire …

The nuclear matrix has been implicated in several cellular processes, including DNA
replication, transcription, and RNA processing. In particular, transcriptional regulation is …

S100A4 is an EF-hand type calcium-binding protein that regulates tumor metastasis and a
variety of cellular processes via interaction with different target proteins. Here we report that …

We previously identified novel S100A8/A9 receptors, extracellular matrix metalloproteinase
inducer (EMMPRIN), melanoma cell adhesion molecule (MCAM), activated leukocyte cell …