Measurement of autoantibodies using multiplex methodology in patients with systemic lupus erythematosus

JG Hanly, K Thompson, G McCurdy, L Fougere… - Journal of …, 2010 - Elsevier
Autoantibodies are central to the diagnosis and assessment of systemic lupus
erythematosus (SLE). A recent technique for the measurement of autoantibodies utilizes …

Comparison between multiplex assays for autoantibody detection in systemic lupus erythematosus

JG Hanly, L Su, V Farewell, MJ Fritzler - Journal of immunological methods, 2010 - Elsevier
The performance of immunoassays for the detection of autoantibodies is of critical
importance to the diagnosis and assessment of patients with systemic lupus erythematosus …

The homogeneous multiplexed system-a new method for autoantibody profile in systemic lupus erythematosus

G Zandman-Goddard, B Gilburd, O Shovman… - Journal of Immunology …, 2005 - hindawi.com
Systemic lupus erythematosus (SLE) is a multi-systemic autoimmune disease leading to
immunological aberrations and excessive multiple autoantibody production. The aim of this …

Revisiting autoantibody profiles in systemic lupus erythematosus.

IH Olhoffer, SL Peng, J Craft - The Journal of Rheumatology, 1997 - europepmc.org
Objective To obtain more definitive assays of the spectrum of soluble autoantigens targeted
by individual patients with systemic lupus erythematosus (SLE) and to determine whether …

Comparison of autoantibody specificities between traditional and bead‐based assays in a large, diverse collection of patients with systemic lupus erythematosus and …

BF Bruner, JM Guthridge, R Lu, G Vidal… - Arthritis & …, 2012 - Wiley Online Library
Objective Replacement of standard immunofluorescence methods with bead‐based assays
for antinuclear antibody (ANA) testing is a new clinical option. The aim of this study was to …

Information on diagnosis and management of systemic lupus erythematosus derived from the routine measurement of 8 nuclear autoantibodies.

GP Ignat, AC Rat, JJ Sychra, J Vo, J Varga… - The Journal of …, 2003 - jrheum.org
OBJECTIVE: To determine the value of routine measurement of a panel of 8 nuclear
autoantibodies (ANA/8) for the diagnosis and management of patients with systemic lupus …

Sensitivity and specificity of autoantibody tests in the differential diagnosis of lupus nephritis

U Heidenreich, G Mayer, M Herold, W Klotz… - Lupus, 2009 - journals.sagepub.com
Several studies have investigated the potential of various autoantibody tests in the diagnosis
of systemic lupus erythematosus (SLE). Many lupus patients initially present with …

Autoantibodies in systemic lupus erythematosus: comparison of historical and current assessment of seropositivity

A Ippolito, DJ Wallace, D Gladman, PR Fortin… - Lupus, 2011 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is characterized by multiple autoantibodies and
complement activation. Recent studies have suggested that anti-nuclear antibody (ANA) …

Clinical value of an integrated ELISA system for the detection of 6 autoantibodies (ssDNA, dsDNA, Sm, RNP/Sm, SSA, and SSB).

CJ Froelich, J Wallman, JL Skosey… - The Journal of …, 1990 - europepmc.org
An ELISA panel assay (ANA/6) which simultaneously detects IgG autoantibodies against 6
antigens (ssDNA, dsDNA, Sm, RNP/Sm, SSA, and SSB) was evaluated with sera from 98 …

An analysis of clinical disease activity and nephritis‐associated serum autoantibody profiles in patients with systemic lupus erythematosus: a cross‐sectional study

CT Ravirajan, L Rowse, JR MacGowan… - …, 2001 - academic.oup.com
Objective. To establish the correlation between lupus nephritis‐associated autoantibody
levels and the presence/activity of lupus nephritis and global disease activity using cross …