The dysregulation of cell signaling plays a pivotal role in tumorigenesis and progression.
miRNAs have been linked to almost all known aspects of physiological and pathological …

In recent years, microRNAs (miRNAs) have been identified as mediators of tumour
suppression and stress responses exerted by the p53 tumour suppressor. p53-regulated …

Recent findings position microRNA (miRNAs) as novel key players in regulating expression
of protein-coding genes by interfering with the stability and/or translation of specific target …

During the past ten years, microRNAs (miRNAs) have been shown to play a more significant
role in the formation and progression of cancer diseases than previously thought. With an …

p53 is one of the most frequently mutated tumor suppressors. It regulates protein-coding
genes and noncoding RNAs involved in many cellular processes, functioning predominantly …

MicroRNAs (miRNAs) are endogenous and small non-coding RNAs that have been
identified as mediators of tumor suppression as well as stress responses mediated by p53 …

MicroRNAs (miRNAs) participate in most aspects of cellular differentiation and homeostasis,
and consequently have roles in many pathologies, including cancer. These small non …

The tumor suppressor p53 pathway, whose alterations are highly associated with all types of
human cancers, plays an essential role in preventing tumor development and progression …

In the recent years, microRNAs (miRNAs) were identified as important components of the
signaling cascades that mediate and regulate tumor suppression exerted by p53. This …

Tumor suppressor p53 plays a central role in tumor suppression. As a transcription factor,
p53 mainly exerts its tumor suppressive function through transcriptional regulation of many …