Investigations of cancer-specific gene rearrangements have increased our understanding of
human neoplasia and led to the use of the rearrangements in pathological diagnosis of …

Follicular thyroid carcinomas (FTC) arise through oncogenic pathways distinct from those
involved in the papillary histotype. Recently, at (2; 3)(q13; p25) rearrangement, which …

Chromosomal translocations encoding fusion oncoproteins are common in hematological
malignancies, sarcomas, and papillary thyroid carcinomas. A recent study of follicular thyroid …

A series of 88 conventional follicular and Hürthle cell thyroid tumors were analyzed for
RAS mutations and PAX8-PPARγ rearrangements using molecular methods and for galectin …

Recently, a translocation t (2; 3)(q13; p25), leading to the formation of a chimeric PAX8-
peroxisome proliferator-activated receptor (PPAR) γ1 oncogene, was detected in follicular …

Peroxisome proliferator-activated receptor gamma (PPARγ) has previously been implicated
in the pathogenesis of follicular thyroid carcinoma (FTC), where a translocation with PAX8 …

The occurrence of the PAX8-PPAR γ fusion gene is thought to be restricted to follicular
tumors (adenomas and carcinomas) of the thyroid (FTA and FTC). Using interphase …

Background: PAX8/PPARγ rearrangement is a common genetic alteration in follicular thyroid
carcinoma (FTC) and has been reported with variable frequency in papillary thyroid …

Abstract A PAX8-PPARγ rearrangement has been recently identified in follicular thyroid
carcinomas, but not in follicular adenomas or other thyroid tumors. We report here the …

Context: The clinicopathological characteristics and the molecular features of the follicular
variant of papillary thyroid carcinoma (FVPTC) remain controversial. Objective/Design …