The recent paper by Soravia et al1 describes two kindreds with thyroid carcinoma
associated with familial adenomatous polyposis (FAP). The former included three and the …

Thyroid cancer derived from follicular cells is the most common endocrine malignancy. The
past decade has seen progress in our understanding of the pathogenesis of the various …

The molecular etiology of follicular thyroid tumors is largely unknown, rendering the
diagnostics of these tumors challenging. The somatic alterations present in these tumors …

The underlying genetic events associated with follicular thyroid tumorigenesis are still ill
defined. In this study, we performed a screening for chromosome imbalances by …

Background: Molecular markers associated with thyroid malignancy are increasingly being
used as differential diagnostic tools for thyroid nodules. However, little has been reported …

Papillary thyroid carcinoma usually presents as a multifocal disease; and tumors often recur
in the contralateral thyroid lobe, raising questions concerning their clonal origins. The …

Point mutations in BRAF are genetic hallmarks of papillary thyroid carcinoma (PTC). In this
retrospective study, we examined thyroid aspirates and corresponding paraffin-embedded …

In this study we aimed at investigating the incidence and the role of 3p deletions, particularly
at the 3p25∼ pter region, in follicle cell-derived thyroid neoplasms, by using loss of …

Context: The BRAF V600E mutation (BRAF-MUT) confers an aggressive phenotype in
papillary thyroid carcinoma, but unidentified additional genomic abnormalities may be …

In this study we have characterized chromosomal imbalances in a panel of 29 parathyroid
carcinomas using comparative genomic hybridization (CGH). The most frequently detected …