DISCUSSION Specific cytogenetic abnormalities may involve balanced chromosomal
translocations, which lead to gene fusions and chimeric proteins with gene regulatory …

Recurrent genetic abnormalities are important prognostic markers in acute myeloid
leukemias (AML). The World Health Organization classification recognizes 7 categories of …

The classification of acute myeloid leukemia (AML) recognizes a subgroup of diseases with
recurring genetic abnormalities. Translocation (15; 17) is the marker of acute promyelocitic …

Discussion: Some 60 cases of AML with t (7; 11)(p15; p15) have been reported.
Interestingly, most of the cases involved Asians, especially Japan and China. As the …

Background: Acute myeloid leukemia (AML) is a heterogeneous group of malignant
neoplasm of hematopoietic disorders characterized by an abnormal proliferation of myeloid …

Objective To investigate the clinical and laboratory features of acute myeloid leukemia
(AML) with t (11; 12)(p15; q13) translocation. Methods Two cases of AML with t (11; 12)(p15; …

The t (7; 11)(p15; p15) translocation is a recurrent genetic abnormality associated with acute
myelogenous leukemia (AML). The translocation results in a fusion between the nucleoporin …

We report a patient with acute myeloid leukemia (AML) and t (3; 21; 8)(q21; q22; q22). This
translocation has not been previously described in de novo or relapsed AML. The patient is …

Because an increasing number of chromosomal aberrations have been detected in the
patients with acute leukemia, cytogenetic findings have become more valuable in …

More than 50% of adult patients with acute myeloid leukemia (AML) carry chromosome
abnormalities, like t (8; 21)(q22; q22), t (15; 17), t (8; 21) inv (16) or t (16; 16). t (10; 17) …