A library comprising 44 diversely substituted aurones derivatives was synthesized by
straightforward aldol condensation reactions of benzofuranones and the appropriately …

Neglected parasitic diseases remain a major public health issue worldwide, especially in
tropical and subtropical areas. Human parasite diversity is very large, ranging from protozoa …

Since ancient times gold and its complexes have been used as therapeutics against
different diseases. In modern medicine gold drugs have been applied for the treatment of …

A series of both mono-and dinuclear gold (I) phosphine complexes containing monoanionic
seleno-and thiosemicarbazones as ligands were prepared and fully characterized by …

Four gold (I) complexes conceived as anticancer agents were synthesized by reacting [Au
(PEt3) Cl] and [Au (PPh3) Cl] with ligands derived from δ‐d‐gluconolactone. The ligands' …

Phosphines are the most studied ligands on gold-based metallodrugs, whereas N-
heterocyclic carbenes (NHCs) have been emerging in the past years as potential alternative …

Despite recent encouraging advances against the disease, malaria remains a major public
health problem affecting almost half a billion people and killing almost a million per annum …

The limited chemical stability of gold (III)-based compounds in physiological environment
has been a challenge in drug discovery, and organometallic chemistry might provide the …

Gold and its complexes have long been known to display unique biological and medicinal
properties. Extensive cell-based (in vitro) and animal (in vivo) studies have revealed the …

Leishmaniasis is a set of severe parasitic diseases for which only a limited number of
effective drugs are available, including two antimony-based agents (sodium stibogluconate …