Bioinorganic applications of gold and platinum coordination compounds: a brief historical overview and recent advances in 2017
REF de Paiva, PP Corbi - International Journal of Advances in …, 2018 - journalamb.com
Gold-based metallodrugs have been used for a wide variety of medical–related applications.
Although none of them have reached clinical trials, many compounds show potential for a …
Although none of them have reached clinical trials, many compounds show potential for a …
Chemical biology of anticancer gold (III) and gold (I) complexes
T Zou, CT Lum, CN Lok, JJ Zhang… - Chemical Society Reviews, 2015 - pubs.rsc.org
Gold complexes have recently gained increasing attention in the design of new metal-based
anticancer therapeutics. Gold (III) complexes are generally reactive/unstable under …
anticancer therapeutics. Gold (III) complexes are generally reactive/unstable under …
Metal complexes as chemotherapeutic agents against tropical diseases: trypanosomiasis, malaria and leishmaniasis
RA Sánchez-Delgado… - Mini reviews in medicinal …, 2004 - ingentaconnect.com
Parasitic diseases represent a major world health problem with very limited therapeutic
options, most of the available treatments being decades old and suffering from limited …
options, most of the available treatments being decades old and suffering from limited …
Heteroleptic (S^ C)-cyclometallated gold (III) complexes as novel antiviral agents
M Balsera-Manzanero, RG Soengas… - Heliyon, 2024 - cell.com
Despite the increasingly widespread clinical impact of adenovirus (HAdV) infections in
healthy individuals and the associated high morbidity in immunosuppressed patients …
healthy individuals and the associated high morbidity in immunosuppressed patients …
Medicinal Au (I) compounds targeting urease as prospective antimicrobial agents: Unveiling the structural basis for enzyme inhibition
A few gold compounds were recently found to show antimicrobial properties in vitro, holding
great promise for the discovery of new drugs to overcome antibiotic resistance. Here, the …
great promise for the discovery of new drugs to overcome antibiotic resistance. Here, the …
Advances in alkynyl gold complexes for use as potential anticancer agents
Z Yang, G Jiang, Z Xu, S Zhao, W Liu - Coordination Chemistry Reviews, 2020 - Elsevier
Gold-based anticancer agents have gained the widespread attention of medicinal inorganic
chemists due to their unique chemical properties and strong antiproliferative potency …
chemists due to their unique chemical properties and strong antiproliferative potency …
Organometallic Gold(III) Complex [Au(Hdamp)(L14)]+ (L1 = SNS-Donating Thiosemicarbazone) as a Candidate to New Formulations against Chagas Disease
CD Lopes, B Possato, APS Gaspari… - ACS Infectious …, 2019 - ACS Publications
Chagas disease remains a serious public health concern with unsatisfactory treatment
outcomes due to strain-specific drug resistance and various side effects. To identify new …
outcomes due to strain-specific drug resistance and various side effects. To identify new …
Gold(I) ion and the phosphine ligand are necessary for the anti-Toxoplasma gondii activity of auranofin
CI Ma, JA Tirtorahardjo, SS Schweizer… - Microbiology …, 2024 - Am Soc Microbiol
Auranofin, an FDA-approved drug for rheumatoid arthritis, has emerged as a promising
antiparasitic medication in recent years. The gold (I) ion in auranofin is postulated to be …
antiparasitic medication in recent years. The gold (I) ion in auranofin is postulated to be …
Gold (III) complexes in the oncological preclinical arena: from aminoderivatives to peptidomimetics
C Nardon, D Fregona - Current topics in medicinal chemistry, 2016 - ingentaconnect.com
In the last decade, we have been developing some gold (III) derivatives showing interesting
antitumor properties and reduced systemic and renal toxicity, compared to the clinically …
antitumor properties and reduced systemic and renal toxicity, compared to the clinically …