The purported purpose of this book is to cover new “directions and to update and highlight
important applications of gold complexes.” To achieve this purpose, advances in three …

194Metal complexes have demonstrated to be a promising alternative in the search of new
drugs for the treatment of neglected tropical diseases and, particularly, those caused by …

Human African Trypanosomiasis (HAT), Chagas disease or American Trypanosomiasis
(CD), and leishmaniases are protozoan infections produced by trypanosomatid parasites …

Three pseudohalide analogues of the established gold drug auranofin (AF hereafter), of
general formula Au (PEt 3) X, ie Au (PEt 3) CN, Au (PEt 3) SCN and Au (PEt 3) N 3 …

Introduction Drugs which are effective on P2Y12 receptor downregulation may be
significantly profitable in more than one way. Firstly, P2Y12 inhibition down regulates HIF1a …

Nowadays, gold compounds constitute a family of very promising experimental agents for
cancer treatment. Indeed, several gold (I) and gold (III) compounds were shown to manifest …

The synthesis of unpresented Gold (I) complexes related to Cinchona alkaloids derivatives
is reported. The main target was the synthesis and biological evaluation of Gold (I)-PPh3 …

Apicomplexian parasite of the genus Plasmodium is the causative agent of malaria, one of
the most devastating, furious and common infectious disease throughout the world …

In the search for novel ligands with efficacy against various diseases, particularly parasitic
diseases, molecular hybridization of organometallic units into biologically active scaffolds …

The use of gold in medicine has a long history. Recent clinical applications include anti-
inflammatory agents for the treatment of rheumatoid arthritis (chrysotherapy), and is currently …