The role of branched-chain amino acids and branched-chain α-keto acid dehydrogenase kinase in metabolic disorders
C Du, WJ Liu, J Yang, SS Zhao, HX Liu - Frontiers in Nutrition, 2022 - frontiersin.org
Branched-chain amino acids (BCAAs), composed of leucine, isoleucine, and valine, are
important essential amino acids in human physiology. Decades of studies have revealed …
important essential amino acids in human physiology. Decades of studies have revealed …
The critical role of the branched chain amino acids (BCAAs) catabolism-regulating enzymes, branched-chain aminotransferase (BCAT) and branched-chain α-keto …
A Dimou, V Tsimihodimos, E Bairaktari - International Journal of …, 2022 - mdpi.com
Branched chain amino acids (BCAAs), leucine, isoleucine and valine, are essential amino
acids widely studied for their crucial role in the regulation of protein synthesis mainly through …
acids widely studied for their crucial role in the regulation of protein synthesis mainly through …
Branched chain amino acids: beyond nutrition metabolism
Branched chain amino acids (BCAAs), including leucine (Leu), isoleucine (Ile), and valine
(Val), play critical roles in the regulation of energy homeostasis, nutrition metabolism, gut …
(Val), play critical roles in the regulation of energy homeostasis, nutrition metabolism, gut …
Recent progress on branched-chain amino acids in obesity, diabetes, and beyond
MAB Siddik, AC Shin - Endocrinology and Metabolism, 2019 - synapse.koreamed.org
Branched-chain amino acids (BCAAs) are essential amino acids that are not synthesized in
our body; thus, they need to be obtained from food. They have shown to provide many …
our body; thus, they need to be obtained from food. They have shown to provide many …
Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 …
F Vanweert, P Schrauwen, E Phielix - Nutrition & diabetes, 2022 - nature.com
Branched-chain amino acid (BCAA) catabolism has been considered to have an emerging
role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes (T2D) …
role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes (T2D) …
Metabolic and physiological roles of branched‐chain amino acids
MD Monirujjaman, A Ferdouse - Advances in Molecular Biology, 2014 - Wiley Online Library
Branch chain amino acids (BCAAs) have unique properties with diverse physiological and
metabolic roles. They have functions other than simple nutrition. Different diseases including …
metabolic roles. They have functions other than simple nutrition. Different diseases including …
Role of branched‐chain amino acid–catabolizing enzymes in intertissue signaling, metabolic remodeling, and energy homeostasis
D Biswas, L Duffley, T Pulinilkunnil - The FASEB Journal, 2019 - Wiley Online Library
Beyond their contribution as fundamental building blocks of life, branched‐chain amino
acids (BCAAs) play a critical role in physiologic and pathologic processes. Importantly …
acids (BCAAs) play a critical role in physiologic and pathologic processes. Importantly …
Insulin resistance and the metabolism of branched-chain amino acids
Insulin resistance (IR) is a key pathological feature of metabolic syndrome and subsequently
causes serious health problems with an increased risk of several common metabolic …
causes serious health problems with an increased risk of several common metabolic …
The relationship between branched‐chain amino acid related metabolomic signature and insulin resistance: a systematic review
X Zhao, Q Han, Y Liu, C Sun, X Gang… - Journal of diabetes …, 2016 - Wiley Online Library
Recent studies have shown the positive association between increased circulating BCAAs
(valine, leucine, and isoleucine) and insulin resistance (IR) in obese or diabetic patients …
(valine, leucine, and isoleucine) and insulin resistance (IR) in obese or diabetic patients …
Gut microbiota as the link between elevated BCAA serum levels and insulin resistance
J Gojda, M Cahova - Biomolecules, 2021 - mdpi.com
The microbiota-harboring human gut is an exquisitely active ecosystem that has evolved in a
constant symbiosis with the human host. It produces numerous compounds depending on its …
constant symbiosis with the human host. It produces numerous compounds depending on its …
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