Summary Background High plasma HIV-1 RNA concentrations are associated with
increased risk of HIV-1 transmission. Initiation of antiretroviral therapy (ART) reduces plasma …

Background: Recent studies have estimated the reduction in HIV-1 infectiousness with
antiretroviral therapy (ART), but high-quality studies such as randomized controlled trials …

Background The risk of sexual transmission of HIV-1 is strongly associated with the level of
HIV-1 RNA in plasma making reduction in HIV-1 plasma levels an important target for HIV-1 …

Objectives: To synthesize the evidence on the risk of HIV transmission through unprotected
sexual intercourse according to viral load and treatment with combination antiretroviral …

Objective: To estimate the impact of small changes in plasma levels of HIV-1 RNA on the risk
of heterosexual transmission or disease progression to an AIDS-defining event or death …

Background An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052
trial showed that antiretroviral therapy (ART) prevented more than 96% of genetically linked …

Objective: Combination antiretroviral therapy (ART) decreases the risk of sexual HIV
transmission by suppressing blood and genital HIV RNA concentrations. We sought to …

Background The risk of sexual transmission of HIV from individuals with low-level HIV
viraemia receiving antiretroviral therapy (ART) has important public health implications …

Background Antiretroviral therapy that reduces viral replication could limit the transmission
of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. Methods In nine …

In 2016, the Prevention Access Campaign, a health equity initiative with the goal of ending
the HIV/AIDS pandemic as well as HIV-related stigma, launched the Undetectable …