Delivery of VEGF using collagen‐coated polycaprolactone scaffolds stimulates angiogenesis

S Singh, BM Wu, JCY Dunn - Journal of Biomedical Materials …, 2012 - Wiley Online Library
Establishing sufficient vascularization in scaffold remains a challenge for tissue‐
engineering. To improve angiogenesis, we incorporated vascular endothelial growth factor …

Bioactivation of collagen matrices through sustained VEGF release from PLGA microspheres

C Borselli, F Ungaro, O Oliviero… - … Research Part A: An …, 2010 - Wiley Online Library
The success of any tissue engineering implant relies upon prompt vascularization of the
cellular construct and, hence, on the ability of the scaffold to broadcast specific activation of …

Anti-inflammatory polymeric coatings for implantable biomaterials and devices

AW Bridges, AJ García - Journal of diabetes science and …, 2008 - journals.sagepub.com
Synthetic polymer coatings are used extensively in modern medical devices and implants
because of their material versatility and processability. These coatings are designed for …

In vitro characterization of vascular endothelial growth factor and dexamethasone releasing hydrogels for implantable probe coatings

LW Norton, E Tegnell, SS Toporek, WM Reichert - Biomaterials, 2005 - Elsevier
Anti-fouling hydrogel coatings, copolymers of 2-hydroxyethyl methacrylate, 1-vinyl-2-
pyrrolidinone, and polyethylene glycol, were investigated for the purpose of improving …

[HTML][HTML] Polymer-free corticosteroid dimer implants for controlled and sustained drug delivery

K Battiston, I Parrag, M Statham, D Louka… - Nature …, 2021 - nature.com
Polymeric drug carriers are widely used for providing temporal and/or spatial control of drug
delivery, with corticosteroids being one class of drugs that have benefitted from their use for …

Controlled release from coated polymer microparticles embedded in tissue-engineered scaffolds

Y Hu, JO Hollinger, KG Marra - Journal of drug targeting, 2001 - Taylor & Francis
The controlled release of proteins in tissue-engineered implants is being examined with the
potential application to improve vascularization and hasten tissue growth. Bovine serum …

Temporal progression of the host response to implanted poly (ethylene glycol)‐based hydrogels

AD Lynn, AK Blakney, TR Kyriakides… - Journal of Biomedical …, 2011 - Wiley Online Library
Abstract Poly (ethylene glycol)(PEG) hydrogels hold great promise as in vivo cell carriers for
tissue engineering. To ensure appropriate performance of these materials when implanted …

3D systems delivering VEGF to promote angiogenesis for tissue engineering

A Des Rieux, B Ucakar, BPK Mupendwa… - Journal of controlled …, 2011 - Elsevier
In most cases, vascularization is the first requirement to achieve tissue regeneration. The
delivery from implants of angiogenic factors, like VEGF, has been widely investigated for …

Vascular endothelial growth factor and dexamethasone release from nonfouling sensor coatings affect the foreign body response

LW Norton, HE Koschwanez… - … research Part A, 2007 - Wiley Online Library
Vascular endothelial growth factor (VEGF) and dexamethasone (DX) release from hydrogel
coatings were examined as a means to modify tissue inflammation and induce …

Using bimodal MRI/fluorescence imaging to identify host angiogenic response to implants

A Berdichevski, H Simaan Yameen… - Proceedings of the …, 2015 - National Acad Sciences
Therapies that promote angiogenesis have been successfully applied using various
combinations of proangiogenic factors together with a biodegradable delivery vehicle. In this …