We sought to develop bioactive hydrogels to facilitate arterial healing, eg, after balloon
angioplasty. Toward this end, we developed a new class of proteolytically sensitive …

Tunable/sustained drug loading/releasing are of significance in addressing low cytotoxicity,
long-term performance, and localized mild healing response in biomedical applications …

A major limitation with current tissue‐engineering approaches is creating functionally
vascularized constructs that can successfully integrate with the host; this often leads to …

Tissue-engineered organs and implants hold promise for the replacement of damaged and
diseased organs. However, the foreign body response (FBR) is a major obstacle that …

Dexamethasone (Dex)-loaded implants were prepared by poly (d, l-lactic acid)(PLA) and
poly (ethylene glycol)-block-poly (propylene glycol)-block-poly (ethylene glycol) copolymer …

Angiogenesis is an organized series of events, beginning with vessel destabilization,
followed by endothelial cell re-organization, and ending with vessel maturation. The …

Poly (lactic-co-glycolic acid)(PLGA) microsphere has been a useful tool in delivering
therapeutic drugs and biologically active proteins. In this study, a covered porous PLGA …

A possible alternative for immunosuppression is a microencapsulation technique using
hydrogels, which have been utilized for cell immobilization and drug delivery systems …

Crosslinked hyaluronan (HA) hydrogels preloaded with two cytokine growth factors, vascular
endothelial growth factor (VEGF) and keratinocyte growth factor (KGF), were employed to …

Implant materials need to be highly biocompatible to avoid inflammation in clinical practice.
Although biodegradable polymeric implants can eliminate the need for a second surgical …