Strategies to engineer bone tissue have focused on either:(1) the use of scaffolds for
osteogenic cell transplantation or as conductive substrates for guided bone regeneration; or …

The in vivo host response to two gelatin-based hydrogel systems of varying crosslinking
modalities and loaded with the anti-inflammatory agent dexamethasone sodium phosphate …

Abstract Poly (ethylene glycol)(PEG) hydrogels, modified with RGD, are promising platforms
for cell encapsulation and tissue engineering. While these hydrogels offer tunable …

Therapeutic vascularization remains a significant challenge in regenerative medicine
applications. Whether the goal is to induce vascular growth in ischemic tissue or scale up …

Timely vascularization is essential for optimal performance of bone regenerative constructs.
Vascularization is efficiently stimulated by vascular endothelial growth factor (VEGF), a …

Hydrogels composed of crosslinked, chemically modified hyaluronic acid (HA), gelatin (Gtn)
and heparin (Hp) were preloaded with vascular endothelial growth factor (VEGF) …

Biodegradable polymers have been extensively used in biomedical applications, ranging
from regenerative medicine to medical devices. However, the acidic byproducts resulting …

Immune homeostasis is maintained by a precise balance between effector immune cells and
regulatory immune cells. Chronic deviations from immune homeostasis, driven by a greater …

Injectable hydrogels are suitable for local cell delivery to the subcutaneous space, but the
lack of vasculature remains a limiting factor. Previously we demonstrated that biomaterials …

Scaffolds have a key role in the clinical success of tissue engineering for the regeneration of
damaged tissues. Their bio-performance is often described as the extent to which they can …