Rapid and controlled vascularization within scaffolds remains one of the key limitations in
tissue engineering applications. This study describes the fabrication and characterization of …

There is an increasing need to control the type, quantity, and timing of growth factors
released during tissue healing. Sophisticated delivery systems offering the ability to deliver …

Inflammation is intimately related to the pathogenesis of numerous acute and chronic
diseases like cardiovascular disease, inflammatory bowel disease, rheumatoid arthritis, and …

Influencing the host immune system via implantable cell-delivery devices has the potential to
reduce inflammation at the transplant site and increase the likelihood of tissue acceptance …

The performance of implantable biomedical devices is impeded by the foreign-body
reaction, which results in formation of a dense collagenous capsule that blocks mass …

Creating a long‐lasting and functional vasculature represents one of the most fundamental
challenges in tissue engineering. VEGF has been widely accepted as a potent angiogenic …

The retention and sustained activity of therapeutic proteins at delivery sites are goals of
regenerative medicine. Vascular endothelial growth factor (VEGF) has significant potential in …

Inflammatory responses to implanted biomedical devices elicit a foreign body fibrotic
reaction that limits device integration and performance in various biomedical applications …

Macrophages are major upstream regulators of the inflammatory response to implanted
biomaterials. Sequential functions of distinct macrophage phenotypes are essential to the …

In vivo profile of vascular endothelial growth factor (VEGF) release from collagen hydrogels
was investigated comparing that of hydrogel degradation while angiogenesis induced by the …