Chronic treatment of the spontaneously hypertensive rat with captopril attenuates responses to noradrenaline in vivo but not in vitro

J Atkinson, M Sonnay, M Sautel, AK Fouda - … -Schmiedeberg's archives of …, 1987 - Springer
We have studied the attenuation by captopril of sympathetic neurotransmission in
spontaneously hypertensive rats. Captopril (4 mg/kg for 15–17 days or 20 mg/kg for 4 days) …

Hypotensive action of captopril in spontaneously hypertensive and normotensive rats. Interference with neurogenic vasoconstriction.

DP Clough, R Hatton, JR Keddie, MG Collis - Hypertension, 1982 - Am Heart Assoc
The effects of captopril and angiotensin II on adrenergic neurotransmission have been
studied in spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY). In a pithed …

Evidence for prejunctional inhibition of norepinephrine release by captopril in spontaneously hypertensive rats

MJ Antonaccio, L Kerwin - European Journal of Pharmacology, 1980 - Elsevier
Pretreatment of spontaneously hypertensive rats (SHR) with the converting enzyme inhibitor
captoril (10 or 100 mg/kg po) had no effect on pressor responses to angiotensin II or …

Attenuation by captopril of pressor responses to sympathetic stimuli: effects of procedures reducing activity of the renin‐angiotensin system

ALA Boura, MP Rechtman… - Journal of Autonomic …, 1983 - Wiley Online Library
1 Low doses (0.1–1.0 mg/kg) of the converting enzyme inhibitor captopril given
intravenously to pithed rats were followed by long lasting falls in systolic and diastolic …

Sympathetic function in spontaneously hypertensive rats after chronic administration of captopril

KH Berecek, KA Kirk, S Nagahama… - American Journal of …, 1987 - journals.physiology.org
The cardiovascular effects of electrical stimulation of the posterior hypothalamus,
intravenous administration of norepinephrine (NE), and direct sympathetic nerve stimulation …

Altered vascular reactivity and baroreflex sensitivity induced by chronic central administration of captopril in the spontaneously hypertensive rat.

KH Berecek, T Okuno, S Nagahama, S Oparil - Hypertension, 1983 - Am Heart Assoc
Previous studies from our laboratory have shown that chronic intracerebroventricular
administration of captopril attenuates the development of hypertension in the spontaneously …

Attenuation by captopril of pressor responses to peripheral sympathetic nerve stimulation in rats is abolished after bilateral nephrectomy and during mineralocorticoid …

ALA Boura, SCG Hui, EJN Ishac… - Clinical and …, 1983 - Wiley Online Library
Intravenous administration of captopril (0.1‐0.3 mg/kg) to normotensive pithed rats, with or
without unilateral nephrectomy, was followed by a sustained fall in arterial blood pressure …

Captopril increases norepinephrine spillover rate in conscious spontaneously hypertensive rats.

YJ Kuo, TK Keeton - Journal of Pharmacology and Experimental …, 1991 - ASPET
These experiments were designed to test the hypothesis that the antihypertensive action of
the converting enzyme inhibitor captopril in conscious spontaneously hypertensive rats is …

Hypotensive effects of captopril administered centrally in intace conscious spontanously hypertensive rats and peripherally in anephric anaesthetized spontaneously …

JS Hutchinson, FA Mendelsohn - Clinical and Experimental …, 1980 - europepmc.org
1. The hypotensive response to captopril in anaesthetized spontanously hypertensive rats
(SHR) is not modified by bilateral nephrectomy performed 1 or 24 h previously. 2 …

Comparison of the acute and chronic hemodynamic effects of captopril and guanethidine in spontaneously hypertensive rats

RA Ferrone, CL Heran… - Clinical and Experimental …, 1980 - Taylor & Francis
The present study compared the hemodynamic effects of captopril with those of
guanethidine as well as with a combination of these two drugs in conscious male …