Serotonin 5-HT2A and 5-HT6 receptors in the prefrontal cortex of Alzheimer and normal aging patients
Background It has been hypothesized that alterations of the serotonergic system contribute
to neuropsychiatric symptoms in Alzheimer disease (AD). Cellular expressions of the two …
to neuropsychiatric symptoms in Alzheimer disease (AD). Cellular expressions of the two …
[HTML][HTML] 5-HT7 receptors in Alzheimer's disease
Even though the involvement of serotonin (5-hydroxytryptamine; 5-HT) and its receptors in
Alzheimer's disease (AD) is widely accepted, data on the expression and the role of 5-HT 7 …
Alzheimer's disease (AD) is widely accepted, data on the expression and the role of 5-HT 7 …
Differential involvement of 5-HT1B/1D and 5-HT6 receptors in cognitive and non-cognitive symptoms in Alzheimer's disease
M Garcia-Alloza, WD Hirst, CP Chen… - …, 2004 - nature.com
Growing evidence suggests that a compromised serotonergic system plays an important role
in the pathophysiology of Alzheimer's disease (AD). We assessed the expression of 5-HT …
in the pathophysiology of Alzheimer's disease (AD). We assessed the expression of 5-HT …
Hippocampal 5-HT1A receptor expression changes in prodromal stages of Alzheimer's disease: Beneficial or deleterious?
M Verdurand, L Zimmer - Neuropharmacology, 2017 - Elsevier
There is increasing evidence that the serotonergic system is highly dysfunctional in
Alzheimer's disease (AD), and this could be related to cognitive impairments associated with …
Alzheimer's disease (AD), and this could be related to cognitive impairments associated with …
Reduced serotonin 5-HT1A receptor binding in the temporal cortex correlates with aggressive behavior in Alzheimer disease
MKP Lai, SWY Tsang, PT Francis, MM Esiri, J Keene… - Brain research, 2003 - Elsevier
Previous studies have implicated brain serotonin 5-HT1A receptors in several CNS
functions, including cognition, mood and emotional states. In Alzheimer disease (AD) …
functions, including cognition, mood and emotional states. In Alzheimer disease (AD) …
Involvement of an altered 5-HT 6 receptor function in behavioral symptoms of Alzheimer's disease
B Marcos, M Garcia-Alloza, FJ Gil-Bea… - Journal of …, 2008 - content.iospress.com
We studied the hypothesis that disturbances in 5-HT6 receptor function in the temporal
cortex may contribute to clinical symptoms of Alzheimer's disease (AD). 5-HT6 density and 5 …
cortex may contribute to clinical symptoms of Alzheimer's disease (AD). 5-HT6 density and 5 …
A review of the literature on neuroimaging of serotoninergic function in Alzheimer's disease and related disorders
E Salmon - Journal of neural transmission, 2007 - Springer
Behavioural and psychological disorders are frequent not only in frontotemporal dementia
(FTD), but also in Alzheimer's disease (AD), and many of them are related to serotoninergic …
(FTD), but also in Alzheimer's disease (AD), and many of them are related to serotoninergic …
Differential involvement of hippocampal serotonin1A receptors and re-uptake sites in non-cognitive behaviors of Alzheimer's disease
MKP Lai, SW Tsang, MM Esiri, PT Francis… - …, 2011 - Springer
Rationale Previous studies have shown extensive serotonergic deficits in the hippocampus
of Alzheimer's disease (AD) patients. However, it is unclear whether such deficits play a role …
of Alzheimer's disease (AD) patients. However, it is unclear whether such deficits play a role …
Loss of serotonin 5-HT2A receptors in the postmortem temporal cortex correlates with rate of cognitive decline in Alzheimer's disease
MK Lai, SW Tsang, JT Alder, J Keene, T Hope… - …, 2005 - Springer
Rationale Previous studies have demonstrated reductions of serotonin 5-HT 2A receptors in
the neocortex of Alzheimer's disease (AD) patients. However, it is unclear whether such …
the neocortex of Alzheimer's disease (AD) patients. However, it is unclear whether such …
Reduced 5-HT2A receptor binding in patients with mild cognitive impairment
Previous studies of patients with Alzheimer's disease (AD) have described reduced brain
serotonin 2A (5-HT2A) receptor density. It is unclear whether this abnormality sets in early in …
serotonin 2A (5-HT2A) receptor density. It is unclear whether this abnormality sets in early in …