The serotonin receptor gene (5‐HT2A) has been reported to be a susceptible factor in
behavioral and psychological symptoms of dementia (BPSD) in Alzheimer's disease (AD) …

The prefrontal cortex (PFC) is enriched in several serotonin receptors, including 5-HT1A-R,
5-HT2A-R, and 5-HT3-R. These receptors modulate PFC activity due to their expression in …

Abstract Rationale. Serotonin (5-HT) autoreceptors regulate extracellular 5-HT levels and
have been suggested to limit the effects of acute treatment with selective serotonin reuptake …

5-HT4 receptors are widely distributed in both peripheral and central nervous systems
where they couple, via a G-protein, to the activation of adenylate cyclase. In the brain, the …

We investigated the binding parameters, ie the maximum binding capacity (B max) and the
dissociation constant (K d), of [3 H] 8-hydroxy-2-(di-N-propylamino) tetralin ([3 H] 8-OH …

Rationale Information is sparse on neurotransmitter deficiencies in frontotemporal dementia
(FTD), in particular with reference to distinct histological subgroups and Alzheimer's disease …

The present study was designed to investigate the distribution of serotonin 5-HT1A receptor
protein (5-HT1A-immunoreactivity) and its localization within cortical pyramidal neurons of …

Serotonin (5-HT) neuron and neurotransmitter loss in normal aging and neuropsychiatric
diseases of late life may contribute to behavioral changes commonly observed in the elderly …

Several neurochemical in vitro and in vivo imaging studies have been aimed at
characterizing the localization of serotonin receptors and transporters in the human brain. In …

Hyperphagia and associated eating changes occur frequently in Alzheimer's disease (AD)
and lead to considerable morbidity. However, the neurochemical basis for these …