Long‐term safety and efficacy in patients with uncontrolled partial‐onset seizures treated with adjunctive lacosamide: results from a Phase III open‐label extension …
A Husain, S Chung, E Faught, J Isojarvi, C McShea… - …, 2012 - Wiley Online Library
Purpose: To evaluate the long‐term (up to 5 years exposure) safety and efficacy of
lacosamide as adjunctive therapy in patients with uncontrolled partial‐onset seizures taking …
lacosamide as adjunctive therapy in patients with uncontrolled partial‐onset seizures taking …
Patterns of antiseizure medication utilization in the Human Epilepsy Project
Objective This study was undertaken to ascertain the natural history and patterns of
antiseizure medication (ASM) use in newly diagnosed focal epilepsy patients who were …
antiseizure medication (ASM) use in newly diagnosed focal epilepsy patients who were …
Lacosamide as adjunctive therapy for partial-onset epileptic seizures: a review of the clinical and economic literature
S Simoens - Current medical research and opinion, 2011 - Taylor & Francis
Objective: This article provides a short but comprehensive pharmacotherapeutic update of
adjunctive therapy with lacosamide for partial-onset seizures in adult patients. Research …
adjunctive therapy with lacosamide for partial-onset seizures in adult patients. Research …
Clinical impact of the dose and blood concentration of lacosamide in Japanese pediatric patients with epilepsy: a cohort study
N Ishikawa, Y Eguchi, H Izumo, Y Tateishi, H Tani… - Epilepsy & Behavior, 2022 - Elsevier
Purpose The relationship between treatment efficacy/tolerability and the dose/blood
concentration of lacosamide (LCM) was investigated in a clinical cohort of Japanese …
concentration of lacosamide (LCM) was investigated in a clinical cohort of Japanese …
Efficacy, safety, and tolerability of lacosamide monotherapy versus controlled-release carbamazepine in patients with newly diagnosed epilepsy: a phase 3 …
Background Further options for monotherapy are needed to treat newly diagnosed epilepsy
in adults. We assessed the efficacy, safety, and tolerability of lacosamide as a first-line …
in adults. We assessed the efficacy, safety, and tolerability of lacosamide as a first-line …
Adjunctive lacosamide—5 years' clinical experience
LJ Stephen, K Kelly, P Parker, MJ Brodie - Epilepsy research, 2014 - Elsevier
Summary Purpose In 2008, lacosamide (LCM) was licensed in Europe for the adjunctive
treatment of focal-onset seizures. At that time a prospective audit was initiated at the Western …
treatment of focal-onset seizures. At that time a prospective audit was initiated at the Western …
The Effectivety, Safety and Tolerability Profile of Lacosamide Therapy in Refractory Epilepsy: Premarketing Experience
F Genc, FEU Tokuc, G Akca, Y Aydemir, G Kutlu… - 2014 - acikerisim.mu.edu.tr
Objectives: Lacosamide is a novel antiepileptic drug used in partial refractory epilepsy
patients. Methods: We searched retrospectively 1100 patients who have follow up in Antalya …
patients. Methods: We searched retrospectively 1100 patients who have follow up in Antalya …
[HTML][HTML] The retention of lacosamide in patients with epilepsy and intellectual disability in three specialised institutions
J Brenner, HJM Majoie, S van Beek, JA Carpay - Seizure, 2017 - Elsevier
Purpose We describe the effectiveness of lacosamide as adjunctive therapy in patients with
epilepsy and an intellectual disability. This information is relevant, as few data exist …
epilepsy and an intellectual disability. This information is relevant, as few data exist …
[HTML][HTML] Long-term efficacy and safety of lacosamide monotherapy in the treatment of partial-onset seizures: a multicenter evaluation
BG Giráldez, R Toledano, I García-Morales… - Seizure, 2015 - Elsevier
Purpose The goal of this study is to report the efficacy and tolerability of lacosamide (LCM)
monotherapy, as first-line and conversion regimens, in the treatment of patients with partial …
monotherapy, as first-line and conversion regimens, in the treatment of patients with partial …
Six months of postmarketing experience with adjunctive lacosamide in patients with pharmacoresistant focal epilepsy at a tertiary epilepsy center in Germany
We report our 6months of experience with adjunctive lacosamide in 25 patients with
pharmacoresistant focal epilepsy. Baseline characteristics of our patients were similar to …
pharmacoresistant focal epilepsy. Baseline characteristics of our patients were similar to …