Efficacy and tolerability of lacosamide monotherapy in elderly patients with newly diagnosed epilepsy: subgroup analysis of a non-inferiority trial versus controlled …
Objective: To evaluate efficacy and tolerability of lacosamide monotherapy in elderly
patients (≥ 65 years) with newly-diagnosed epilepsy. Background: Primary results of the …
patients (≥ 65 years) with newly-diagnosed epilepsy. Background: Primary results of the …
[HTML][HTML] Tolerability and efficacy of lacosamide and controlled-release carbamazepine monotherapy in patients with newly diagnosed epilepsy and concomitant …
B Schmitz, S Dimova, Y Zhang, D Chellun… - Epilepsy Research, 2020 - Elsevier
Psychiatric comorbidities are common in patients with epilepsy. A double-blind noninferiority
monotherapy trial (SP0993; NCT01243177) enrolled newly diagnosed patients (≥ 16 years) …
monotherapy trial (SP0993; NCT01243177) enrolled newly diagnosed patients (≥ 16 years) …
Lacosamide efficacy and tolerability in clinical practice–Post marketing analysis from a single dedicated epilepsy center
MD Baker, BW Abou-Khalil, A Arain, P Tummala… - Clinical Neurology and …, 2018 - Elsevier
Objectives Post marketing analysis of anti-epileptic drug (AED) efficacy and tolerability is of
great value to the clinician since it is more representative of clinical practice than clinical trial …
great value to the clinician since it is more representative of clinical practice than clinical trial …
Dose effects of lacosamide as add-on therapy for partial-onset seizure in adult
D Chen, Y Lin, T Chen, Q Zhang, Y Lin, Y Si… - Neurological …, 2016 - Springer
The objective of the study was to evaluate the dose effects of lacosamide on the efficacy and
safety as adjunctive therapy for partial-onset seizure in adults. We searched online …
safety as adjunctive therapy for partial-onset seizure in adults. We searched online …
[HTML][HTML] Lacosamide as adjunctive therapy in refractory epilepsy in adults: a systematic review
V Paquette, C Culley, ED Greanya, MHH Ensom - Seizure, 2015 - Elsevier
Purpose To review the evidence for efficacy and safety of lacosamide in adult patients with
refractory epilepsy and refractory status epilepticus (RSE). Methods A systematic literature …
refractory epilepsy and refractory status epilepticus (RSE). Methods A systematic literature …
Use of extended-release and immediate-release anti-seizure medications with a long half-life to improve adherence in epilepsy: a guide for clinicians
BE Gidal, J Ferry, L Reyderman, JE Piña-Garza - Epilepsy & Behavior, 2021 - Elsevier
Poor adherence to anti-seizure medications (ASMs) is associated with breakthrough
seizures and potentially increased toxicity in patients with epilepsy. Extended-release (ER) …
seizures and potentially increased toxicity in patients with epilepsy. Extended-release (ER) …
Antiseizure medication adherence trajectories in Medicare beneficiaries with newly treated epilepsy
Objective This study was undertaken to characterize trajectories of antiseizure medication
(ASM) adherence in adults with newly treated epilepsy and to determine predictors of …
(ASM) adherence in adults with newly treated epilepsy and to determine predictors of …
Efficacy upon 12-weeks after achievement of maximal dose and tolerability of lacosamide as an adjunctive therapy in epilepsy: Real world clinical experience
RS Chang, HKK Lui, HTC Lui, CYW Leung… - Journal of the …, 2020 - Elsevier
Lacosamide (LCM) is a new generation antiepileptic drug. It has only been available in Asia
in recent years. A retrospective study at two hospitals in Hong Kong was performed to …
in recent years. A retrospective study at two hospitals in Hong Kong was performed to …
[HTML][HTML] The impact of side effects on long-term retention in three new antiepileptic drugs
HP Bootsma, L Ricker, YA Hekster, J Hulsman… - Seizure, 2009 - Elsevier
OBJECTIVE: To determine long-term retention, percentage of patients withdrawing because
of adverse events, percentage of patients achieving seizure freedom, safety profile of the …
of adverse events, percentage of patients achieving seizure freedom, safety profile of the …