[引用][C] Lacosamide: efficacy and safety as oral adjunctive treatment in adults with partial onset seizures
S Chung, M Sperling, V Biton, G Krauss, M Beaman… - Epilepsia, 2007
[PDF][PDF] The Role of Add-On Lacosamide Therapy in the Treatment of Focal Onset Epilepsy.
Objectives: The aim of this study was to retrospectively evaluate the efficacy and safety of
lacosamide (200-300-400 mg/day) as adjunct treatment in patients with uncontrolled focal …
lacosamide (200-300-400 mg/day) as adjunct treatment in patients with uncontrolled focal …
Seizure freedom and plasma levels of newer generation antiseizure medications
I Aícua‐Rapún, P André, AO Rossetti… - Acta Neurologica …, 2021 - Wiley Online Library
Objectives Contrary to older antiseizure medications (ASM), correlation between plasma
levels and seizure freedom is not well defined for newer generation ASM. We assessed …
levels and seizure freedom is not well defined for newer generation ASM. We assessed …
Tolerability and efficacy of lacosamide monotherapy in patients with newly-diagnosed epilepsy and psychiatric comorbidities: Post hoc analysis of a prospective …
B Schmitz, MR Newton, S Dimova, Y Zhang… - Neurology, 2017 - AAN Enterprises
Objective: To evaluate the tolerability and efficacy of lacosamide monotherapy in patients
with newly-diagnosed epilepsy and psychiatric comorbidities. Background: Psychiatric …
with newly-diagnosed epilepsy and psychiatric comorbidities. Background: Psychiatric …
Examining the clinical utility of lacosamide: pooled analyses of three phase II/III clinical trials
S Chung, E Ben-Menachem, MR Sperling… - CNS drugs, 2010 - Springer
Background: Lacosamide is an antiepileptic drug (AED) approved for the adjunctive
treatment of partial-onset seizures in adults. Completed phase II/III clinical trials of …
treatment of partial-onset seizures in adults. Completed phase II/III clinical trials of …
Long-term effectiveness and safety of lacosamide as adjunctive therapy in children and adolescents with refractory epilepsy: a real-world study
T Zhao, L Yu, H Zhang, J Yu, J Feng, T Wang, Y Sun… - BMC pediatrics, 2023 - Springer
Purpose The effectiveness and tolerability of lacosamide (LCM) among Chinese children
and adolescents with refractory epilepsy has not yet been established. Therefore, the …
and adolescents with refractory epilepsy has not yet been established. Therefore, the …
Antiseizure medication adherence trajectories in Medicare beneficiaries with newly treated epilepsy
Objective This study was undertaken to characterize trajectories of antiseizure medication
(ASM) adherence in adults with newly treated epilepsy and to determine predictors of …
(ASM) adherence in adults with newly treated epilepsy and to determine predictors of …
[引用][C] Lacosamide: an interim evaluation of long-term safety and efficacy as oral adjunctive therapy in subjects with partial-onset seizures
W Rosenfeld, NB Fountain, G Kaubrys, L Heinzen… - Epilepsia, 2007
Clinical experience combined with therapeutic drug monitoring of lacosamide
T Svendsen, E Brodtkorb, A Baftiu… - Acta Neurologica …, 2020 - Wiley Online Library
Objective Lacosamide (LCM) is an antiepileptic drug (AED) with insufficient clinical
experience in patients with intellectual disability (ID). They often have more severe epilepsy …
experience in patients with intellectual disability (ID). They often have more severe epilepsy …
Clinical features associated with placebo response in refractory focal epilepsy
D Schmidt, S Beyenburg, J D'Souza, K Stavem - Epilepsy & Behavior, 2013 - Elsevier
For clinical trial design and for clinical practice, it is of importance to assess factors
associated with placebo response in patients with refractory epilepsy. We determined factors …
associated with placebo response in patients with refractory epilepsy. We determined factors …