The inter-relationship between delirium and dementia: the importance of delirium prevention

TG Fong, SK Inouye - Nature Reviews Neurology, 2022 - nature.com
Delirium and dementia are two frequent causes of cognitive impairment among older adults
and have a distinct, complex and interconnected relationship. Delirium is an acute …

Recurrent delirium over 12 months predicts dementia: results of the Delirium and Cognitive Impact in Dementia (DECIDE) study

SJ Richardson, DHJ Davis, BCM Stephan… - Age and …, 2021 - academic.oup.com
Background Delirium is common, distressing and associated with poor outcomes. Previous
studies investigating the impact of delirium on cognitive outcomes have been limited by …

A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank

ES Oh, O Akeju, MS Avidan… - Alzheimer's & …, 2020 - Wiley Online Library
Delirium is an acute disorder of attention and cognition. It occurs across the life span, yet it is
particularly common among older adults, and is closely linked with underlying …

Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study

DHJ Davis, G Muniz Terrera, H Keage, T Rahkonen… - Brain, 2012 - academic.oup.com
Recent studies suggest that delirium is associated with risk of dementia and also
acceleration of decline in existing dementia. However, previous studies may have been …

Delirium accelerates cognitive decline in Alzheimer disease

TG Fong, RN Jones, P Shi, ER Marcantonio, L Yap… - Neurology, 2009 - AAN Enterprises
Objective: To examine the impact of delirium on the trajectory of cognitive function in a
cohort of patients with Alzheimer disease (AD). Methods: A secondary analysis of data …

Introduction: Elucidating the pathophysiology of delirium and the interrelationship of delirium and dementia

SK Inouye, L Ferrucci - The Journals of Gerontology Series A …, 2006 - academic.oup.com
DELIRIUM, defined as an acute decline of attention and cognitive function, represents a
common and potentially devastating problem for hospitalized older persons. With …

Delirium: a marker of vulnerability in older people

G Bellelli, JS Brathwaite, P Mazzola - Frontiers in aging neuroscience, 2021 - frontiersin.org
Delirium is an acute neuropsychiatric syndrome and one of the most common presenting
symptoms of acute medical illnesses in older people. Delirium can be triggered by a single …

Delirium superimposed on dementia: a systematic review

DM Fick, JV Agostini, SK Inouye - Journal of the American …, 2002 - Wiley Online Library
Delirium in a patient with preexisting dementia is a common problem that may have serious
complications and poor prognostic implications. The purpose of this paper was to conduct a …

Delirium in the elderly: a comprehensive review

V Mittal, S Muralee, D Williamson… - American Journal of …, 2011 - journals.sagepub.com
Delirium is a common neuropsychiatric syndrome in the elderly characterized by concurrent
impairments in cognition and behaviors. The etiologies for delirium are often multifactorial …

[HTML][HTML] Worsening cognitive impairment and neurodegenerative pathology progressively increase risk for delirium

DHJ Davis, DT Skelly, C Murray, E Hennessy… - The American journal of …, 2015 - Elsevier
Background Delirium is a profound neuropsychiatric disturbance precipitated by acute
illness. Although dementia is the major risk factor this has typically been considered a binary …