[HTML][HTML] Considerations of timing post-ovariectomy in mice and rats in studying anxiety-and depression-like behaviors associated with surgical menopause in women
JF Rodríguez-Landa - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
Menopause is a clinical term that indicates the end of the reproductive period of women that
occurs naturally; however, it can be induced by bilateral oophorectomy, which is commonly …
occurs naturally; however, it can be induced by bilateral oophorectomy, which is commonly …
[HTML][HTML] Ovariectomy results in variable changes in nociception, mood and depression in adult female rats
Decline in the ovarian hormones with menopause may influence somatosensory, cognitive,
and affective processing. The present study investigated whether hormonal depletion alters …
and affective processing. The present study investigated whether hormonal depletion alters …
Long-term ovariectomy increases anxiety-and despair-like behaviors associated with lower Fos immunoreactivity in the lateral septal nucleus in rats
A Puga-Olguín, JF Rodríguez-Landa… - Behavioural Brain …, 2019 - Elsevier
In woman, surgical menopause is associated with anxiety and depression symptoms.
Ovariectomy in rats has been proposed as an experimental model of surgical menopause …
Ovariectomy in rats has been proposed as an experimental model of surgical menopause …
Prolame ameliorates anxiety and spatial learning and memory impairment induced by ovariectomy in rats
I Nissen, FS Estrada, AT Nava-Kopp, C Irles… - Physiology & …, 2012 - Elsevier
N-(3-hydroxy-1, 3, 5 (10) estratrien-17beta-yl)-3-hydroxypropylamine (17β aminoestrogen,
prolame) is a steroidal compound with weak estrogen-related trophic-proliferative effects in …
prolame) is a steroidal compound with weak estrogen-related trophic-proliferative effects in …
Decreased voluntary activity and amygdala levels of serotonin and dopamine in ovariectomized rats
N Izumo, Y Ishibashi, M Ohba, T Morikawa… - Behavioural brain …, 2012 - Elsevier
Estrogen is involved in numerous activities in the brain, such as learning, memory, fear,
anxiety and mood. However, little is known about the pathways involved in the effects of …
anxiety and mood. However, little is known about the pathways involved in the effects of …
[HTML][HTML] Linking alterations in estrogen receptor expression to memory deficits and depressive behavior in an ovariectomy mouse model
DC Baek, JY Kang, JS Lee, EJ Lee, CG Son - Scientific Reports, 2024 - nature.com
The high risk of neurological disorders in postmenopausal women is an emerging medical
issue. Based on the hypothesis of altered estrogen receptors (ERα and β) after the decline of …
issue. Based on the hypothesis of altered estrogen receptors (ERα and β) after the decline of …
[HTML][HTML] Effects of long-term ovariectomy on anxiety and behavioral despair in rats
G De Chaves, M Moretti, AA Castro, W Dagostin… - Physiology & …, 2009 - Elsevier
Clinical and pre-clinical findings point to the critical role of ovarian hormones in modulating
anxiety and depressive symptoms in female. However, few studies investigated the effects of …
anxiety and depressive symptoms in female. However, few studies investigated the effects of …
[HTML][HTML] Ovariectomy induces microglial cell activation and inflammatory response in rat prefrontal cortices to accelerate the chronic unpredictable stress-mediated …
F Ge, H Yang, W Lu, H Shi, Q Chen, Y Luo… - BioMed Research …, 2020 - hindawi.com
Perimenopausal women are associated with increased risks of depression and anxiety,
which may be potentially related to the lack of ovarian hormone with antidepression activity …
which may be potentially related to the lack of ovarian hormone with antidepression activity …
Anxiolytic property of estrogen related to the changes of the monoamine levels in various brain regions of ovariectomized rats
J Pandaranandaka, S Poonyachoti… - Physiology & …, 2006 - Elsevier
Anxiety is a symptom reflecting the dysregulation of monoaminergic neurotransmitters which
may be modulated by estrogen. In our current study, we investigated the effects of chronic …
may be modulated by estrogen. In our current study, we investigated the effects of chronic …
[HTML][HTML] The Phytoestrogen Genistein Produces Similar Effects as 17β-Estradiol on Anxiety-Like Behavior in Rats at 12 Weeks after Ovariectomy
JF Rodríguez-Landa, J Cueto-Escobedo… - BioMed Research …, 2017 - hindawi.com
The phytoestrogen genistein produces anxiolytic-like effects in ovariectomized rats, which
highlights its potential therapeutic effect in ameliorating anxiety in surgical menopausal …
highlights its potential therapeutic effect in ameliorating anxiety in surgical menopausal …