Identification of glyceraldehyde-3-phosphate dehydrogenase of epithelial cells as a second molecule that binds to Porphyromonas gingivalis fimbriae

HT Sojar, RJ Genco - FEMS Immunology & Medical …, 2005 - academic.oup.com
Binding of Porphyromonas gingivalis to the host cells is an essential step in the
pathogenesis of periodontal disease. P. gingivalis binds to and invades epithelial cells, and …

Involvement of integrins in fimbriae‐mediated binding and invasion by Porphyromonas gingivalis

Ö Yilmaz, K Watanabe, RJ Lamont - Cellular microbiology, 2002 - Wiley Online Library
Interaction between the major fimbriae of Porphyromonas gingivalis and gingival epithelial
cells is important for bacterial adhesion and invasion. In this study, we identified integrins as …

Isolation and characterization of a minor fimbria from Porphyromonas gingivalis

N Hamada, HT Sojar, MI Cho, RJ Genco - Infection and immunity, 1996 - Am Soc Microbiol
We have discovered two distinctly different fimbriae expressed by the same Porphyromonas
gingivalis strain. The construction of a fimA mutant of P. gingivalis ATCC 33277 has …

Fimbriae of Porphyromonas gingivalis induce opsonic antibodies that significantly enhance phagocytosis and killing by human polymorphonuclear leukocytes

Q Fan, T Sims, H Sojar, R Genco… - Oral microbiology and …, 2001 - Wiley Online Library
Porphyromonas gingivalis has been strongly implicated in the pathogenesis of human
periodontitis. Fimbriae mediate adherence and colonization of the oral cavity by this …

Porphyromonas gingivalis Minor Fimbriae Are Required for Cell-Cell Interactions

X Lin, J Wu, H Xie - Infection and immunity, 2006 - Am Soc Microbiol
Two distinctive types of fimbriae have been identified in Porphyromonas gingivalis. In this
report, we demonstrate that minor fimbriae are involved in P. gingivalis autoaggregation and …

Interactions of Porphyromonas gingivalis with epithelial cells

MJ Duncan, S Nakao, Z Skobe, H Xie - Infection and immunity, 1993 - Am Soc Microbiol
The invasion of gingival epithelial cells by certain pathogenic periodontal bacteria may
account for their presence within diseased gingival tissue. To dissect the initial steps of a …

Porphyromonas gingivalis Fimbriae Induce Adhesion of Monocytic Cell Line U937 to Endothelial Cells

K Hirose, E Isogai, I Ueda - Microbiology and immunology, 2000 - Wiley Online Library
This study used the human monocytic cell line U937 to examine whether or not
Porphyromonas gingivalis fimbriae could induce the adhesion of monocytes to endothelial …

Adhesion of Porphyromonas gingivalis fimbriae to human gingival cell line Ca9‐22

K Hirose, E Isogai, H Mizugai… - Oral microbiology and …, 1996 - Wiley Online Library
In this study, we examined the effects of selected environmental factors on the adhesion of
Porphyromonas gingivalis fimbriae, an important structure involved in attachment of the …

Invasion of Epithelial Cells and Proteolysis of Cellular Focal Adhesion Components by Distinct Types of Porphyromonas gingivalis Fimbriae

I Nakagawa, H Inaba, T Yamamura, T Kato… - Infection and …, 2006 - Am Soc Microbiol
Porphyromonas gingivalis fimbriae are classified into six types (types I to V and Ib) based on
the fimA genes encoding FimA (a subunit of fimbriae), and they play a critical role in …

Purification of major fimbrial proteins of Porphyromonas gingivalis

JY Lee, HT Sojar, A Amano, RJ Genco - Protein expression and purification, 1995 - Elsevier
Binding of Porphyromonas gingivalis to pellicle-coated teeth is mediated to a large extent by
fimbrillin, a major structural subunit of fimbriae. A simple and efficient method for purifying …