Anti-inflammatory therapy in chronic disease: challenges and opportunities
A number of widespread and devastating chronic diseases, including atherosclerosis, type 2
diabetes, and Alzheimer's disease, have a pathophysiologically important inflammatory …
diabetes, and Alzheimer's disease, have a pathophysiologically important inflammatory …
Inflammation bares a dark side
J Couzin-Frankel - 2010 - science.org
Inflammation Bares a Dark Side | Science news careers commentary Journals Science Science
brought to you byGoogle Indexer Log in science science advances science immunology science …
brought to you byGoogle Indexer Log in science science advances science immunology science …
Targeting inflammation in atherosclerosis—from experimental insights to the clinic
O Soehnlein, P Libby - Nature reviews Drug discovery, 2021 - nature.com
Atherosclerosis, a dominant and growing cause of death and disability worldwide, involves
inflammation from its inception to the emergence of complications. Targeting inflammatory …
inflammation from its inception to the emergence of complications. Targeting inflammatory …
Resolution of inflammation: the beginning programs the end
CN Serhan, J Savill - Nature immunology, 2005 - nature.com
Acute inflammation normally resolves by mechanisms that have remained somewhat
elusive. Emerging evidence now suggests that an active, coordinated program of resolution …
elusive. Emerging evidence now suggests that an active, coordinated program of resolution …
Anti-inflammatory therapeutics for the treatment of atherosclerosis
IF Charo, R Taub - Nature reviews Drug discovery, 2011 - nature.com
Atherosclerosis is the primary cause of heart disease and stroke and is thus the underlying
pathology of the leading causes of death in the western world. Although risk can be reduced …
pathology of the leading causes of death in the western world. Although risk can be reduced …
Regulation of inflammation in chronic disease
Growing evidence suggests a close link between inflammation and many chronic health
conditions including diabetes, metabolic syndrome, cardiovascular disease, cancer …
conditions including diabetes, metabolic syndrome, cardiovascular disease, cancer …
Dampening inflammation
PM Henson - Nature immunology, 2005 - nature.com
This series of reviews addresses mechanisms whereby inflammation can be reduced,
turned off or perhaps prevented, both in the context of natural dampening processes as well …
turned off or perhaps prevented, both in the context of natural dampening processes as well …
Inflammatory resolution: new opportunities for drug discovery
Abstract Treatment of inflammatory diseases today is largely based on interrupting the
synthesis or action of mediators that drive the host's response to injury. Non-steroidal anti …
synthesis or action of mediators that drive the host's response to injury. Non-steroidal anti …
Anti-inflammatory agents: present and future
CA Dinarello - Cell, 2010 - cell.com
Inflammation involving the innate and adaptive immune systems is a normal response to
infection. However, when allowed to continue unchecked, inflammation may result in …
infection. However, when allowed to continue unchecked, inflammation may result in …
Targeting inflammation in coronary artery disease
RA Harrington - New England Journal of Medicine, 2017 - Mass Medical Soc
For more than 20 years, our understanding of the biology of atherosclerosis has
incorporated the so-called inflammatory hypothesis. 1, 2 Inflammatory cells and signals drive …
incorporated the so-called inflammatory hypothesis. 1, 2 Inflammatory cells and signals drive …
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