The role of circRNAs in cancers

LP Zhu, YJ He, JC Hou, X Chen, SY Zhou… - Bioscience …, 2017 - portlandpress.com
Circular RNAs (circRNAs) are recently regarded as a naturally forming family of widespread
and diverse endogenous noncoding RNAs (ncRNAs) that may regulate gene expression in …

Circular RNAs: Promising biomarkers for cancer diagnosis and prognosis

G Wei, J Zhu, HB Hu, JQ Liu - Gene, 2021 - Elsevier
Circular RNAs (circRNAs), a group of non-coding RNA characterized by the presence of
covalent bonds linking 3′ and 5′ ends, act as miRNA sponges to participate in the …

Circular RNAs in human cancer

Y Wang, Y Mo, Z Gong, X Yang, M Yang, S Zhang… - Molecular cancer, 2017 - Springer
CircRNAs are a novel type of RNAs. With the newly developed technology of next-
generation sequencing (NGS), especially RNA-seq technology, over 30,000 circRNAs have …

New molecular mechanisms and clinical impact of circRNAs in human cancer

G Fontemaggi, C Turco, G Esposito, S Di Agostino - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) belong to a new class of non-coding RNAs
implicated in cellular physiological functions but also in the evolution of various human …

Circular RNAs: emerging cancer biomarkers and targets

Y Zhang, W Liang, P Zhang, J Chen, H Qian… - Journal of Experimental …, 2017 - Springer
CircRNAs are a class of RNA molecules that structurally form closed loops. CircRNAs are
abundant in eukaryotic transcripts and show certain levels of tissue and cell specificity …

Circular RNAs serve as novel biomarkers and therapeutic targets in cancers

S Fang, J Pan, C Zhou, H Tian, J He… - Current Gene …, 2019 - ingentaconnect.com
Circular RNAs (circRNAs) are a class of non-coding RNAs (ncRNAs) that structurally form
closed loops without 5'-end cap and 3'-end poly (A) tail unlike linear RNAs. CircRNAs are …

Recent progress of circular RNAs in different types of human cancer: Technological landscape, clinical opportunities and challenges

AR Sharma, S Banerjee… - International …, 2022 - spandidos-publications.com
Circular RNAs (circRNAs) are a novel class of endogenous non‑coding RNAs that have
been recently regarded as functionally active. CircRNAs are remarkably stable and known to …

Emerging epigenetic regulation of circular RNAs in human cancer

J Wu, X Qi, L Liu, X Hu, J Liu, J Yang, J Yang… - … Therapy-Nucleic Acids, 2019 - cell.com
Circular RNAs (circRNAs) are novel members of the noncoding RNA family. Their
characteristic covalent closed-loop structure endows circRNAs that are much more stable …

Emerging function and potential diagnostic value of circular RNAs in cancer

X Cui, J Wang, Z Guo, M Li, M Li, S Liu, H Liu, W Li… - Molecular cancer, 2018 - Springer
As a novel class of endogenous RNAs, circRNAs, have a covalently closed continuous loop,
with neither a 5'to 3'polarity, nor a polyadenylated tail. Numerous circRNAs have been …

Function and clinical significance of circRNAs in solid tumors

Y Geng, J Jiang, C Wu - Journal of hematology & oncology, 2018 - Springer
Circular RNA (circRNA) is a new type of endogenous non-coding RNAs (ncRNAs). circRNA
regulates gene expression in many biological processes, and it also participates in the …