[HTML][HTML] Brain region specific glucagon-like peptide-1 receptors regulate alcohol-induced behaviors in rodents

D Vallöf, AL Kalafateli, E Jerlhag - Psychoneuroendocrinology, 2019 - Elsevier
Abstract Glucagon-like peptide 1 (GLP-1), an incretin hormone that reduces food intake, was
recently established as a novel regulator of alcohol-mediated behaviors. Clinically available …

[HTML][HTML] The glucagon-like peptide 1 analogue Exendin-4 attenuates alcohol mediated behaviors in rodents

E Egecioglu, P Steensland, I Fredriksson… - …, 2013 - Elsevier
Development of alcohol use disorders largely depends on the effects of alcohol on the brain
reward systems. Emerging evidence indicate that common mechanisms regulate food and …

[HTML][HTML] Gut peptide GLP-1 and its analogue, Exendin-4, decrease alcohol intake and reward

RH Shirazi, SL Dickson, KP Skibicka - PloS one, 2013 - journals.plos.org
Glucagon-like-peptide-1 (GLP-1) is a gut-and neuro-peptide with an important role in the
regulation of food intake and glucose metabolism. Interestingly, GLP-1 receptors (GLP-1R) …

The glucagon-like peptide 1 receptor agonist Exendin-4 decreases relapse-like drinking in socially housed mice

M Thomsen, D Dencker, G Wörtwein, P Weikop… - Pharmacology …, 2017 - Elsevier
Abstract Glucagon-like peptide-1 (GLP-1) is a gut peptide that regulates food intake and
glucose metabolism. GLP-1 is also produced and released in the brain, and GLP-1 …

[HTML][HTML] Brain site-specific inhibitory effects of the GLP-1 analogue exendin-4 on alcohol intake and operant responding for palatable food

KJ Colvin, HS Killen, MJ Kanter, MC Halperin… - International Journal of …, 2020 - mdpi.com
Approximately 14.4 million Americans are experiencing alcohol use disorder (AUD) and
about two-thirds of people who experience drug addiction will relapse, highlighting the need …

Glucagon‐like peptide‐1 receptor signaling in the ventral tegmental area reduces alcohol self‐administration in male rats

TN Dixon, GP McNally, ZY Ong - Alcoholism: Clinical and …, 2020 - Wiley Online Library
Background The misuse and abuse of alcohol is a major public health issue. However,
available treatments are limited with variable efficacy. Recently, preclinical studies show that …

[HTML][HTML] The glucagon-like peptide 1 analogue, exendin-4, attenuates the rewarding properties of psychostimulant drugs in mice

E Egecioglu, JA Engel, E Jerlhag - PloS one, 2013 - journals.plos.org
Glucagon-like peptide 1 (GLP-1) is an incretine hormone that controls consummatory
behavior and glucose homeostasis. It is released in response to nutrient ingestion from the …

The glucagon‐like peptide 1 receptor agonist liraglutide attenuates the reinforcing properties of alcohol in rodents

D Vallöf, P Maccioni, G Colombo, M Mandrapa… - Addiction …, 2016 - Wiley Online Library
The incretin hormone, glucagon‐like peptide 1 (GLP‐1), regulates gastric emptying, glucose‐
dependent stimulation of insulin secretion and glucagon release, and GLP‐1 analogs are …

[HTML][HTML] Glucagon-like peptide-1 receptors within the nucleus of the solitary tract regulate alcohol-mediated behaviors in rodents

D Vallöf, J Vestlund, E Jerlhag - Neuropharmacology, 2019 - Elsevier
The ability of glucagon-like peptide-1 (GLP-1) to reduce food intake involves activation of
GLP-1 receptors (GLP-1R) in the nucleus of the solitary tract (NTS). It has also been …

[HTML][HTML] GLP-1 signaling and alcohol-mediated behaviors; preclinical and clinical evidence

E Jerlhag - Neuropharmacology, 2018 - Elsevier
Alcohol addiction, affecting approximately four percent of the population, contributes
significantly to the global burden of diseases and is a substantial cost to the society. The …