Background Among patients in whom childhood cancer was diagnosed in the 1970s and
1980s, 18% of those who survived for 5 years died within the subsequent 25 years. In recent …

Background The proportion of pediatric and adolescent cancer patients surviving 5 years
has increased during the past four decades. This growing population of survivors remains at …

PURPOSE: Survivors of childhood and adolescent cancer are at risk for long-term effects of
disease and treatment. The Childhood Cancer Survivor Study assessed overall and cause …

Importance Advances in childhood and adolescent cancer treatment have been associated
with increased rates of cure during the past 3 decades; however, improvement in adult life …

Importance Cancer treatments are associated with subsequent neoplasms in survivors of
childhood cancer. It is unknown whether temporal changes in therapy are associated with …

The Childhood Cancer Survivor Study (CCSS) has assembled the largest cohort to date for
assessment of late mortality. Vital status and cause of death of all patients eligible for …

Survivors of childhood and adolescent cancer are at risk for long‐term effects of disease and
treatment. The Childhood Cancer Survivor Study assessed overall and cause‐specific …

PURPOSE To determine the frequency and patterns of late mortality among long-term
survivors of childhood cancer. MATERIALS AND METHODS Medical records of patients who …

During the past three decades, multi-modality therapy for childhood cancer has resulted in
markedly improved survival. For the period of 1985 to 1997, the fiveyear survival rate for …

Background 5-year survival after childhood cancer does not fully describe life-years lost due
to childhood cancer because there are a large number of deaths occurring beyond 5-years …