Biomaterials for mediation of chemical and biological warfare agents

AJ Russell, JA Berberich, GF Drevon… - Annual review of …, 2003 - annualreviews.org
▪ Abstract Recent events have emphasized the threat from chemical and biological warfare
agents. Within the efforts to counter this threat, the biocatalytic destruction and sensing of …

Fighting nerve agent chemical weapons with enzyme technology

KE LeJeune, BC Dravis, F Yang… - Annals of the New …, 1998 - Wiley Online Library
The extreme toxicity of organophosphorous‐based compounds has been known since the
late 1930s. Starting in the mid‐1940s, many nations throughout the world have been …

Organophosphate skin decontamination using immobilized enzymes

RK Gordon, SR Feaster, AJ Russell… - Chemico-Biological …, 1999 - Elsevier
We previously demonstrated that a combination of cholinesterase (ChE) pre-treatment with
an oxime is an effective measure against soman and sarin. We describe here a novel …

Degradation of organophosphorous nerve agents by enzyme‐polymer nanocomposites: Efficient biocatalytic materials for personal protection and large‐scale …

I Gill, A Ballesteros - Biotechnology and bioengineering, 2000 - Wiley Online Library
The biocatalytic destruction of organophosphates has become an important focus area, as
efficient “clean” technologies are sought for chemical weapons decommissioning …

Enzyme-based additives for paints and coatings

CS McDaniel, J McDaniel, ME Wales… - Progress in Organic …, 2006 - Elsevier
Active enzymes and other active biomolecules sequestered in paints and coatings have the
potential to provide one of the more unique surface coatings yet identified. We report here …

Construction of robust enzyme nanocapsules for effective organophosphate decontamination, detoxification, and protection.

W Wei, J Du, J Li, M Yan, Q Zhu, X Jin… - … (Deerfield Beach, Fla …, 2013 - europepmc.org
Nanocapsules of organophosphorous hydrolase with enhanced enzyme activity and stability
are prepared via in situ polymerization, providing a novel class of nanoparticles for the …

Catalytic degradation of nerve agents

A Zammataro, R Santonocito, A Pappalardo… - Catalysts, 2020 - mdpi.com
Nerve agents (NAs) are a group of highly toxic organophosphorus compounds developed
before World War II. They are related to organophosphorus pesticides, although they have …

Enhanced‐rate biodegradation of organophosphate neurotoxins by immobilized nongrowing bacteria

JW Kim, EI Rainina, WW Mulbry… - Biotechnology …, 2002 - Wiley Online Library
Pesticide wastes generated from livestock dipping operations containing the
organophosphate (OP) insecticide coumaphos (CP) are well suited for disposal by …

The evolution of phosphotriesterase for decontamination and detoxification of organophosphorus chemical warfare agents

AN Bigley, FM Raushel - Chemico-biological interactions, 2019 - Elsevier
The organophosphorus chemical warfare agents were initially synthesized in the 1930's and
are some of the most toxic compounds ever discovered. The standard means of …

Enhancing enzyme stability by construction of polymer–enzyme conjugate micelles for decontamination of organophosphate agents

N Suthiwangcharoen, R Nagarajan - Biomacromolecules, 2014 - ACS Publications
Enhancing the stability of enzymes under different working environments is essential if the
potential of enzyme-based applications is to be realized for nanomedicine, sensing and …