Asymmetric cycloaddition reactions represent a powerful strategy for building up complex
molecular architectures, especially those with medium-sized rings. Herein, we disclose a …

By harnessing an energy transfer process, new photocatalyzed [2+ 2]-cycloadditions
occurring between γ-alkylidene–γ-lactams and unsaturated substrates have been …

Visible light-promoted dearomative [2+ 2] cycloaddition of indole derivatives tethered with
olefins at the N1 position has been considered thermodynamically unfeasible due to the …

Enzymes facilitate chemical conversions through the collective activity of aggregated
components, but the marriage of aggregation‐induced emission (AIE) with molecular …

Thanks to the impressive control that microenvironments within enzymes can have over
substrates, many biological reactions occur with high regio-and stereoselectivity. However …

Photochemical electrocyclization reactions are valued for both their ability to produce
structurally complex molecules and their central role in elucidating fundamental mechanistic …

Regiodivergent asymmetric cycloadditions from the same set of starting materials offer
interesting opportunities for rapid construction of optically active cyclic molecules with …

The efficient generation of high structural complexity, which correlates with the number of
stereocentres, is an important objective in organic synthesis. Ideally, from a perspective of …

Development of a general catalytic and highly efficient method utilizing readily available
precursors for the regio-and stereoselective construction of bioactive natural-product …

Although metal-free cycloadditions of cyclooctynes and azides to give stable 1, 2, 3-triazoles
have found wide utility in chemical biology and material sciences, there is an urgent need for …